Term Information

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Accession
GO:0140507
Name
granzyme-mediated programmed cell death signaling pathway
Ontology
biological_process
Synonyms
granzyme-mediated cell death signaling pathway
Alternate IDs
None
Definition
The series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells. Source: PMID:32299851
Comment
None
History
See term history for GO:0140507 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of granzyme-mediated programmed cell death signaling pathway (GO:0140507)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
granzyme-mediated programmed cell death signaling pathway [BFO:0000050 relation] BFO:0000050  programmed cell death (GO:0012501)
granzyme-mediated programmed cell death signaling pathway [is_a relation] is_a  signal transduction (GO:0007165)
Children of granzyme-mediated programmed cell death signaling pathway (GO:0140507)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
granzyme-mediated apoptotic signaling pathway (GO:0008626) [is_a relation] is_a  granzyme-mediated programmed cell death signaling pathway
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