AmiGO 2: Term Details for "promoter-terminator loop anchoring activity" (GO:0140586)

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Term Information

Accession: GO:0140586
Name: promoter-terminator loop anchoring activity
Ontology: molecular_function
Synonyms: terminator-promoter loop anchoring activity
Alternate IDs: None
Definition: Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop. Source: PMID:19933151
Comment: Note that GO does not separately defines enhancers, since this concept is very close to that of cis-regulatory elements. However the literature refers to 'promoter-enhancer loops' to describe loops that bring together cis-regulatory elements. Note also that while SO defines 'promoter' as the core promoter, here it is used to mean a cis-regulatory element.
History: See term history for GO:0140586 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to promoter-terminator loop anchoring activity (excluding "regulates").; Link to all direct and indirect annotations to promoter-terminator loop anchoring activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for promoter-terminator loop anchoring activity (excluding "regulates").

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GO:0005488 binding
GO:0003674 molecular_function
GO:0097159 organic cyclic compound binding
GO:0003677 DNA binding
GO:0003676 nucleic acid binding
GO:0044877 protein-containing complex binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0060090 molecular adaptor activity
GO:0031490 chromatin DNA binding
GO:0106260 DNA-DNA tethering activity
GO:0140587 chromatin loop anchoring activity
GO:0140586 promoter-terminator loop anchoring activity

Parents of promoter-terminator loop anchoring activity (GO:0140586)

subject	relation	object
promoter-terminator loop anchoring activity	is_a	chromatin loop anchoring activity (GO:0140587)

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