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Accession
GO:0140682
Name
FAD-dependent H3K4me/H3K4me3 demethylase activity
Ontology
molecular_function
Synonyms
histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity, histone H3K4me demethylase activity, histone H3K4me2 demethylase activity
Alternate IDs
None
Definition
Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction. Source: PMID:22473470
Comment
None
History
See term history for GO:0140682 at QuickGO
Chem. react.
has participant hydrogen acceptor
has participant hydrogen donor
has participant formaldehyde
has participant L-lysinium residue
has participant N(6),N(6)-dimethyl-L-lysine(1+) residue
has participant water
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0140682 from QuickGO

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Parents of FAD-dependent H3K4me/H3K4me3 demethylase activity (GO:0140682)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
FAD-dependent H3K4me/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  hydrogen acceptor (CHEBI:13193)
FAD-dependent H3K4me/H3K4me3 demethylase activity [is_a relation] is_a  histone H3K4 demethylase activity (GO:0032453)
FAD-dependent H3K4me/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  hydrogen donor (CHEBI:17499)
FAD-dependent H3K4me/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  formaldehyde (CHEBI:16842)
FAD-dependent H3K4me/H3K4me3 demethylase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
FAD-dependent H3K4me/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  L-lysinium residue (CHEBI:29969)
FAD-dependent H3K4me/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  N(6),N(6)-dimethyl-L-lysine(1+) residue (CHEBI:61976)
FAD-dependent H3K4me/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)

This term has no children.

EC
1.14.99.66
RHEA
60244