Term Information

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Accession
GO:0140684
Name
histone H3K9me2/H3K9me3 demethylase activity
Ontology
molecular_function
Synonyms
histone H3-tri/dimethyl-lysine-9 demethylase activity, histone H3K9me3 demethylase activity, histone H3K9me2 demethylase activity
Alternate IDs
None
Definition
Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. Source: PMID:20531378, PMID:20208542
Comment
None
History
See term history for GO:0140684 at QuickGO
Chem. react.
has participant succinate(2-)
has participant carbon dioxide
has participant formaldehyde
has participant dioxygen
has participant 2-oxoglutarate(2-)
has participant N(6),N(6),N(6)-trimethyl-L-lysine residue
has participant N(6)-methyl-L-lysinium residue
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0140684 from QuickGO

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Parents of histone H3K9me2/H3K9me3 demethylase activity (GO:0140684)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone H3K9me2/H3K9me3 demethylase activity [is_a relation] is_a  histone H3K9 demethylase activity (GO:0032454)
histone H3K9me2/H3K9me3 demethylase activity [RO:0000057 relation] RO:0000057  succinate(2-) (CHEBI:30031)
histone H3K9me2/H3K9me3 demethylase activity [RO:0000057 relation] RO:0000057  carbon dioxide (CHEBI:16526)
histone H3K9me2/H3K9me3 demethylase activity [RO:0000057 relation] RO:0000057  formaldehyde (CHEBI:16842)
histone H3K9me2/H3K9me3 demethylase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
histone H3K9me2/H3K9me3 demethylase activity [RO:0000057 relation] RO:0000057  2-oxoglutarate(2-) (CHEBI:16810)
histone H3K9me2/H3K9me3 demethylase activity [RO:0000057 relation] RO:0000057  N(6),N(6),N(6)-trimethyl-L-lysine residue (CHEBI:61961)
histone H3K9me2/H3K9me3 demethylase activity [is_a relation] is_a  2-oxoglutarate-dependent dioxygenase activity (GO:0016706)
histone H3K9me2/H3K9me3 demethylase activity [RO:0000057 relation] RO:0000057  N(6)-methyl-L-lysinium residue (CHEBI:61929)

This term has no children.

EC
1.14.11.66
RHEA
60200