AmiGO 2: Term Details for "facultative heterochromatin formation" (GO:0140718)

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Term Information

Accession: GO:0140718
Name: facultative heterochromatin formation
Ontology: biological_process
Synonyms: fHC assembly, facultative heterochromatin assembly
Alternate IDs: None
Definition: The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression). In metazoa, this involves the methylation of histone H3K27. Source: PMID:17936700
Comment: Note that facultative heterochromatin can be reprogrammed, as opposed to constitutive heterochromatin which usually cannot be reprogrammed to a transcriptionally-competent state. Note also that facultative heterochromatin formation does not usually involve DNA methylation, while constitutive heterochromatin formation does.
History: See term history for GO:0140718 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to facultative heterochromatin formation (excluding "regulates").; Link to all direct and indirect annotations to facultative heterochromatin formation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for facultative heterochromatin formation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0008152 metabolic process
GO:0048519 negative regulation of biological process
GO:0050794 regulation of cellular process
GO:0009058 biosynthetic process
GO:0071840 cellular component organization or biogenesis
GO:0043170 macromolecule metabolic process
GO:0048523 negative regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0016043 cellular component organization
GO:0009059 macromolecule biosynthetic process
GO:0009892 negative regulation of metabolic process
GO:0009889 regulation of biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0006325 chromatin organization
GO:0010467 gene expression
GO:0009890 negative regulation of biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0006338 chromatin remodeling
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0010468 regulation of gene expression
GO:0040029 epigenetic regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0045814 negative regulation of gene expression, epigenetic
GO:0031507 heterochromatin formation
GO:0140718 facultative heterochromatin formation
GO:0000183 rDNA heterochromatin formation
GO:1902794 siRNA-independent facultative heterochromatin formation
GO:1902795 siRNA-mediated facultative heterochromatin formation

Parents of facultative heterochromatin formation (GO:0140718)

subject	relation	object
facultative heterochromatin formation	is_a	heterochromatin formation (GO:0031507)

Children of facultative heterochromatin formation (GO:0140718)

subject	relation	object
rDNA heterochromatin formation (GO:0000183)	is_a	facultative heterochromatin formation
siRNA-mediated facultative heterochromatin formation (GO:1902795)	is_a	facultative heterochromatin formation
siRNA-independent facultative heterochromatin formation (GO:1902794)	is_a	facultative heterochromatin formation

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