Term Information

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Accession
GO:0140911
Name
pore-forming activity
Ontology
molecular_function
Synonyms
pore forming activity, canonical holin activity, holin activity, pinholin activity
Alternate IDs
GO:0034292, GO:0034290, GO:0034291
Definition
An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death. Source: PMID:34387717, PMID:1406491, PMID:25157079
Comment
None
History
See term history for GO:0140911 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0140911 from QuickGO

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Parents of pore-forming activity (GO:0140911)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pore-forming activity [is_a relation] is_a  molecular_function (GO:0003674)

This term has no children.

TC
1.C