Term Information

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Accession
GO:0140941
Name
histone H4K20me methyltransferase activity
Ontology
molecular_function
Synonyms
histone H4 methyl lysine(20) N-methyltransferase activity (H4-K20 specific), histone H4K20me methylase activity, histone H4-K20 dimethylation, histone H4K20 dimethylation
Alternate IDs
None
Definition
Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethlyated lysine residue at position 20 of histone H4, producing H4K20me2. Source: RHEA:60348
Comment
None
History
See term history for GO:0140941 at QuickGO
Chem. react.
has participant N(6)-methyl-L-lysinium residue
has participant hydron
has participant S-adenosyl-L-methionine zwitterion
has participant N(6),N(6)-dimethyl-L-lysine(1+) residue
has participant S-adenosyl-L-homocysteine zwitterion
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0140941 from QuickGO

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Parents of histone H4K20me methyltransferase activity (GO:0140941)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone H4K20me methyltransferase activity [RO:0000057 relation] RO:0000057  N(6)-methyl-L-lysinium residue (CHEBI:61929)
histone H4K20me methyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
histone H4K20me methyltransferase activity [is_a relation] is_a  histone H4K20 methyltransferase activity (GO:0042799)
histone H4K20me methyltransferase activity [RO:0000057 relation] RO:0000057  S-adenosyl-L-methionine zwitterion (CHEBI:59789)
histone H4K20me methyltransferase activity [RO:0000057 relation] RO:0000057  N(6),N(6)-dimethyl-L-lysine(1+) residue (CHEBI:61976)
histone H4K20me methyltransferase activity [RO:0000057 relation] RO:0000057  S-adenosyl-L-homocysteine zwitterion (CHEBI:57856)

This term has no children.

EC
2.1.1.362
RHEA
60348