AmiGO 2: Term Details for "PAT complex" (GO:0160005)

Accession: GO:0160005
Name: PAT complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the correct folding of multipass membrane proteins in the ER membrane. In human, the substrate-binding Asterix (PAT10, WDR83OS) forms an obligate heterodimer with CCDC47. Source: PMID:33082068, PMID:32814900, PMID:33960686
Comment: PAT complex functions by shielding exposed hydrophilicity of transmembrane domains (TMDs) to prevent premature degradation and promote proper folding and bundling of TMDs.
History: See term history for GO:0160005 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to PAT complex (excluding "regulates").; Link to all direct and indirect annotations to PAT complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for PAT complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
PAT complex	is_a	membrane protein complex (GO:0098796)
PAT complex	BFO:0000050	endoplasmic reticulum membrane (GO:0005789)
PAT complex	is_a	endoplasmic reticulum protein-containing complex (GO:0140534)

This term has no children.

PAT complex