AmiGO 2: Term Details for "hypoxia-inducible factor-proline dioxygenase activity" (GO:0160082)

Accession: GO:0160082
Name: hypoxia-inducible factor-proline dioxygenase activity
Ontology: molecular_function
Synonyms: HIF prolyl hydroxylase, HIF hydroxylase
Alternate IDs: None
Definition: Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit]. Source: PMID:11595184, PMID:11598268
Comment: None
History: See term history for GO:0160082 at QuickGO
Chem. react.: has participant trans-4-hydroxy-L-proline residue; has participant succinate(2-); has participant L-proline residue; has participant 2-oxoglutarate(2-); has participant carbon dioxide; has participant dioxygen
Subset: None
Related: Link to all genes and gene products annotated to hypoxia-inducible factor-proline dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to hypoxia-inducible factor-proline dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for hypoxia-inducible factor-proline dioxygenase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
hypoxia-inducible factor-proline dioxygenase activity	is_a	peptidyl-proline 4-dioxygenase activity (GO:0031545)
hypoxia-inducible factor-proline dioxygenase activity	RO:0000057	trans-4-hydroxy-L-proline residue (CHEBI:61965)
hypoxia-inducible factor-proline dioxygenase activity	RO:0000057	succinate(2-) (CHEBI:30031)
hypoxia-inducible factor-proline dioxygenase activity	RO:0000057	L-proline residue (CHEBI:50342)
hypoxia-inducible factor-proline dioxygenase activity	RO:0000057	2-oxoglutarate(2-) (CHEBI:16810)
hypoxia-inducible factor-proline dioxygenase activity	RO:0000057	carbon dioxide (CHEBI:16526)
hypoxia-inducible factor-proline dioxygenase activity	RO:0000057	dioxygen (CHEBI:15379)

This term has no children.