Term Information

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Accession
GO:1903016
Name
negative regulation of exo-alpha-sialidase activity
Ontology
biological_process
Synonyms
down regulation of N-acylneuraminate glycohydrolase activity, down regulation of acetylneuraminidase activity, down regulation of acetylneuraminyl hydrolase activity, down regulation of alpha-neuraminidase activity, down regulation of exo-alpha-sialidase activity, down regulation of neuraminidase activity, down regulation of sialidase activity, down-regulation of N-acylneuraminate glycohydrolase activity, down-regulation of acetylneuraminidase activity, down-regulation of acetylneuraminyl hydrolase activity, down-regulation of alpha-neuraminidase activity, down-regulation of exo-alpha-sialidase activity, down-regulation of neuraminidase activity, down-regulation of sialidase activity, downregulation of N-acylneuraminate glycohydrolase activity, downregulation of acetylneuraminidase activity, downregulation of acetylneuraminyl hydrolase activity, downregulation of alpha-neuraminidase activity, downregulation of exo-alpha-sialidase activity, downregulation of neuraminidase activity, downregulation of sialidase activity, negative regulation of N-acylneuraminate glycohydrolase activity, negative regulation of acetylneuraminidase activity, negative regulation of acetylneuraminyl hydrolase activity, negative regulation of alpha-neuraminidase activity, negative regulation of neuraminidase activity, negative regulation of sialidase activity, inhibition of N-acylneuraminate glycohydrolase activity, inhibition of acetylneuraminidase activity, inhibition of acetylneuraminyl hydrolase activity, inhibition of alpha-neuraminidase activity, inhibition of exo-alpha-sialidase activity, inhibition of neuraminidase activity, inhibition of sialidase activity
Alternate IDs
None
Definition
Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity. Source: GOC:BHF, GOC:TermGenie, PMID:23544079, GO_REF:0000059, GOC:rl
Comment
human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA)
History
See term history for GO:1903016 at QuickGO
Chem. react.
None
Subset
gocheck_do_not_annotate
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of negative regulation of exo-alpha-sialidase activity (GO:1903016)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of exo-alpha-sialidase activity [is_a relation] is_a  negative regulation of hydrolase activity (GO:0051346)
negative regulation of exo-alpha-sialidase activity [is_a relation] is_a  regulation of exo-alpha-sialidase activity (GO:1903015)
negative regulation of exo-alpha-sialidase activity [RO:0002212 relation] RO:0002212  exo-alpha-sialidase activity (GO:0004308)

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