AmiGO 2: Term Details for "serotonin-activated cation-selective channel complex" (GO:1904602)

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Term Information

Accession: GO:1904602
Name: serotonin-activated cation-selective channel complex
Ontology: cellular_component
Synonyms: 5-HT-3 receptor complex, 5-HT3 receptor complex, 5-hydroxytryptamine receptor 3 complex, 5HT3 receptor complex, serotonin receptor complex
Alternate IDs: None
Definition: A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist. Source: PMID:16116092, GOC:TermGenie, GO_REF:0000088, GOC:bhm
Comment: An example of this is HTR3A in human (P46098) in PMID:16116092 (inferred from direct assay).
History: See term history for GO:1904602 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to serotonin-activated cation-selective channel complex (excluding "regulates").; Link to all direct and indirect annotations to serotonin-activated cation-selective channel complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for serotonin-activated cation-selective channel complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
CARO:0000003 connected anatomical structure
GO:0051179 localization
UBERON:0000465 material anatomical entity
GO:0042221 response to chemical
GO:0050896 response to stimulus
UBERON:0000061 anatomical structure
GO:0070887 cellular response to chemical stimulus
GO:0005575 cellular_component
GO:0051234 establishment of localization
GO:0009719 response to endogenous stimulus
GO:1901698 response to nitrogen compound
GO:0010033 response to organic substance
GO:0006810 transport
GO:0110165 cellular anatomical entity
GO:0009987 cellular process
GO:0071495 cellular response to endogenous stimulus
GO:1901699 cellular response to nitrogen compound
GO:0071310 cellular response to organic substance
GO:0051716 cellular response to stimulus
GO:0015267 channel activity
GO:0003674 molecular_function
GO:0006811 monoatomic ion transport
GO:0010243 response to organonitrogen compound
GO:0055085 transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0065007 biological regulation
GO:0071944 cell periphery
GO:0071417 cellular response to organonitrogen compound
GO:0022836 gated channel activity
GO:0016020 membrane
GO:0006812 monoatomic cation transport
GO:0034220 monoatomic ion transmembrane transport
GO:0022803 passive transmembrane transporter activity
GO:0032991 protein-containing complex
GO:0071867 response to monoamine
GO:0014070 response to organic cyclic compound
GO:1901700 response to oxygen-containing compound
GO:0005215 transporter activity
GO:0071868 cellular response to monoamine stimulus
GO:0071407 cellular response to organic cyclic compound
GO:1901701 cellular response to oxygen-containing compound
GO:0022834 ligand-gated channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0098796 membrane protein complex
GO:0060089 molecular transducer activity
GO:0098655 monoatomic cation transmembrane transport
GO:0005216 monoatomic ion channel activity
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0030594 neurotransmitter receptor activity
GO:0005886 plasma membrane
PR:000050567 protein-containing material entity
GO:0050789 regulation of biological process
GO:0071869 response to catecholamine
GO:0038023 signaling receptor activity
GO:1990351 transporter complex
GO:0007154 cell communication
GO:0071870 cellular response to catecholamine stimulus
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0005261 monoatomic cation channel activity
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0098797 plasma membrane protein complex
GO:0043235 receptor complex
GO:0050794 regulation of cellular process
GO:1903350 response to dopamine
GO:0023052 signaling
GO:0004888 transmembrane signaling receptor activity
GO:1902495 transmembrane transporter complex
GO:0022835 transmitter-gated channel activity
GO:1903351 cellular response to dopamine
GO:0099094 ligand-gated monoatomic cation channel activity
GO:0034702 monoatomic ion channel complex
GO:0098802 plasma membrane signaling receptor complex
GO:0099589 serotonin receptor activity
GO:0007210 serotonin receptor signaling pathway
GO:0007165 signal transduction
GO:0022824 transmitter-gated monoatomic ion channel activity
GO:0034703 cation channel complex
GO:0098878 neurotransmitter receptor complex
GO:0098665 serotonin receptor complex
GO:0022850 serotonin-gated monoatomic cation channel activity
GO:1904602 serotonin-activated cation-selective channel complex

Parents of serotonin-activated cation-selective channel complex (GO:1904602)

subject	relation	object
serotonin-activated cation-selective channel complex	is_a	serotonin receptor complex (GO:0098665)
serotonin-activated cation-selective channel complex	RO:0002216	serotonin receptor signaling pathway (GO:0007210)
serotonin-activated cation-selective channel complex	is_a	neurotransmitter receptor complex (GO:0098878)
serotonin-activated cation-selective channel complex	is_a	cation channel complex (GO:0034703)
serotonin-activated cation-selective channel complex	RO:0002215	serotonin-gated monoatomic cation channel activity (GO:0022850)

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