AmiGO 2: Term Details for "thiazole synthase activity" (GO:1990107)

Term Information

Accession: GO:1990107
Name: thiazole synthase activity
Ontology: molecular_function
Synonyms: 1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O. Source: EC:2.8.1.10, GOC:cjk, RHEA:26297, PMID:22031445
Comment: H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis.
History: See term history for GO:1990107 at QuickGO
Chem. react.: has participant dehydroglycine zwitterion; has participant water; has participant C-terminal N-glycylaminoethanethioic S-acid residue; has participant (R,Z)- 2-carboxylato-4-methyl-5-[(2-phosphonatooxy)ethylidene]-2,5-dihydrothiazole(3-); has participant hydron; has participant C-terminal Gly-Gly(1-) residue; has participant 1-deoxy-D-xylulose 5-phosphate(2-)
Subset: None
Related: Link to all genes and gene products annotated to thiazole synthase activity (excluding "regulates").; Link to all direct and indirect annotations to thiazole synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for thiazole synthase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0009987 cellular process
GO:0071704 organic substance metabolic process
GO:0044281 small molecule metabolic process
GO:0044249 cellular biosynthetic process
GO:0044237 cellular metabolic process
GO:0003674 molecular_function
GO:1901360 organic cyclic compound metabolic process
GO:1901615 organic hydroxy compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0044283 small molecule biosynthetic process
GO:0006766 vitamin metabolic process
GO:0006066 alcohol metabolic process
GO:0003824 catalytic activity
GO:1901362 organic cyclic compound biosynthetic process
GO:1901617 organic hydroxy compound biosynthetic process
GO:1901566 organonitrogen compound biosynthetic process
GO:0072527 pyrimidine-containing compound metabolic process
GO:0006790 sulfur compound metabolic process
GO:0009110 vitamin biosynthetic process
GO:0006767 water-soluble vitamin metabolic process
GO:0046165 alcohol biosynthetic process
GO:0034308 primary alcohol metabolic process
GO:0072528 pyrimidine-containing compound biosynthetic process
GO:0044272 sulfur compound biosynthetic process
GO:0042723 thiamine-containing compound metabolic process
GO:0016740 transferase activity
GO:0042364 water-soluble vitamin biosynthetic process
GO:0034309 primary alcohol biosynthetic process
GO:0006772 thiamine metabolic process
GO:0042724 thiamine-containing compound biosynthetic process
GO:0016782 transferase activity, transferring sulphur-containing groups
GO:0016783 sulfurtransferase activity
GO:0009228 thiamine biosynthetic process
GO:1990107 thiazole synthase activity
GO:1902507 thiazole synthase complex

Parents of thiazole synthase activity (GO:1990107)

subject	relation	object
thiazole synthase activity	is_a	sulfurtransferase activity (GO:0016783)
thiazole synthase activity	RO:0000057	dehydroglycine zwitterion (CHEBI:77846)
thiazole synthase activity	RO:0000057	water (CHEBI:15377)
thiazole synthase activity	RO:0000057	C-terminal N-glycylaminoethanethioic S-acid residue (CHEBI:90619)
thiazole synthase activity	RO:0000057	(R,Z)- 2-carboxylato-4-methyl-5-[(2-phosphonatooxy)ethylidene]-2,5-dihydrothiazole(3-) (CHEBI:62899)
thiazole synthase activity	RO:0000057	hydron (CHEBI:15378)
thiazole synthase activity	BFO:0000050	thiamine biosynthetic process (GO:0009228)
thiazole synthase activity	RO:0000057	C-terminal Gly-Gly(1-) residue (CHEBI:90778)
thiazole synthase activity	RO:0000057	1-deoxy-D-xylulose 5-phosphate(2-) (CHEBI:57792)

Children of thiazole synthase activity (GO:1990107)

subject	relation	object
thiazole synthase complex (GO:1902507)	RO:0002215	thiazole synthase activity

RHEA: 26297