AmiGO 2: Term Details for "intrinsic apoptotic signaling pathway in response to hypoxia" (GO:1990144)

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Term Information

Accession: GO:1990144
Name: intrinsic apoptotic signaling pathway in response to hypoxia
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered. Source: PMID:20436456, GOC:BHF, GOC:mtg_apoptosis, GOC:rl
Comment: None
History: See term history for GO:1990144 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to intrinsic apoptotic signaling pathway in response to hypoxia (excluding "regulates").; Link to all direct and indirect annotations to intrinsic apoptotic signaling pathway in response to hypoxia (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for intrinsic apoptotic signaling pathway in response to hypoxia (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
GO:0009987 cellular process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0050896 response to stimulus
UBERON:0000061 anatomical structure
GO:0008219 cell death
GO:0051716 cellular response to stimulus
GO:0005575 cellular_component
GO:0050789 regulation of biological process
GO:0009628 response to abiotic stimulus
GO:0042221 response to chemical
CL:0000000 cell
GO:0007154 cell communication
GO:0110165 cellular anatomical structure
GO:0070887 cellular response to chemical stimulus
GO:0012501 programmed cell death
GO:0050794 regulation of cellular process
GO:0070482 response to oxygen levels
GO:0023052 signaling
GO:0006915 apoptotic process
GO:0071453 cellular response to oxygen levels
GO:0005622 intracellular anatomical structure
GO:0036293 response to decreased oxygen levels
GO:0006950 response to stress
GO:0007165 signal transduction
GO:0097190 apoptotic signaling pathway
GO:0036294 cellular response to decreased oxygen levels
GO:0033554 cellular response to stress
GO:0035556 intracellular signal transduction
GO:0001666 response to hypoxia
GO:0071456 cellular response to hypoxia
GO:0097193 intrinsic apoptotic signaling pathway
GO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia
GO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway

Parents of intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)

subject	relation	object
intrinsic apoptotic signaling pathway in response to hypoxia	BFO:0000050	cellular response to hypoxia (GO:0071456)
intrinsic apoptotic signaling pathway in response to hypoxia	is_a	intrinsic apoptotic signaling pathway (GO:0097193)
intrinsic apoptotic signaling pathway in response to hypoxia	RO:0002162	Opisthokonta (NCBITaxon:33154)

Children of intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)

subject	relation	object
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903298)	RO:0002212	intrinsic apoptotic signaling pathway in response to hypoxia
regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903297)	RO:0002211	intrinsic apoptotic signaling pathway in response to hypoxia

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