AmiGO 2: Term Details for "RSP5-BUL ubiquitin ligase complex" (GO:1990306)

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Term Information

Accession: GO:1990306
Name: RSP5-BUL ubiquitin ligase complex
Ontology: cellular_component
Synonyms: RSP5-BUL1 complex, RSP5-BUL2 complex
Alternate IDs: None
Definition: A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation. Source: PMID:9931424, GOC:bhm
Comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:9931424
History: See term history for GO:1990306 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to RSP5-BUL ubiquitin ligase complex (excluding "regulates").; Link to all direct and indirect annotations to RSP5-BUL ubiquitin ligase complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RSP5-BUL ubiquitin ligase complex (excluding "regulates").

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GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016755 aminoacyltransferase activity
GO:0140096 catalytic activity, acting on a protein
GO:0005575 cellular_component
GO:0032991 protein-containing complex
PR:000050567 protein-containing material entity
GO:1902494 catalytic complex
GO:0019787 ubiquitin-like protein transferase activity
GO:0140535 intracellular protein-containing complex
GO:1990234 transferase complex
GO:0004842 ubiquitin-protein transferase activity
GO:1990306 RSP5-BUL ubiquitin ligase complex

Parents of RSP5-BUL ubiquitin ligase complex (GO:1990306)

subject	relation	object
RSP5-BUL ubiquitin ligase complex	is_a	intracellular protein-containing complex (GO:0140535)
RSP5-BUL ubiquitin ligase complex	RO:0002215	ubiquitin-protein transferase activity (GO:0004842)
RSP5-BUL ubiquitin ligase complex	is_a	transferase complex (GO:1990234)

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