AmiGO 2: Term Details for "D-2-hydroxyacid dehydrogenase (quinone) activity" (GO:1990464)

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Term Information

Accession: GO:1990464
Name: D-2-hydroxyacid dehydrogenase (quinone) activity
Ontology: molecular_function
Synonyms: (R)-2-hydroxy acid dehydrogenase activity, (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity, (R)-2-hydroxyacid:quinone oxidoreductase activity, D-lactate dehydrogenase (quinone) activity, D-lactate dehydrogenase activity, D-lactate:quinone oxidoreductase activity
Alternate IDs: None
Definition: Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol. Source: PMID:3013300, RHEA:11272, PMID:4582730
Comment: (R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors.
History: See term history for GO:1990464 at QuickGO
Chem. react.: has participant hydroquinones; has participant 1,4-benzoquinones; has participant (2R)-2-hydroxy monocarboxylic acid anion; has participant 2-oxo monocarboxylic acid anion
Subset: None
Related: Link to all genes and gene products annotated to D-2-hydroxyacid dehydrogenase (quinone) activity (excluding "regulates").; Link to all direct and indirect annotations to D-2-hydroxyacid dehydrogenase (quinone) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for D-2-hydroxyacid dehydrogenase (quinone) activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
GO:1990464 D-2-hydroxyacid dehydrogenase (quinone) activity

Parents of D-2-hydroxyacid dehydrogenase (quinone) activity (GO:1990464)

subject	relation	object
D-2-hydroxyacid dehydrogenase (quinone) activity	RO:0000057	hydroquinones (CHEBI:24646)
D-2-hydroxyacid dehydrogenase (quinone) activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor (GO:0016901)
D-2-hydroxyacid dehydrogenase (quinone) activity	RO:0000057	1,4-benzoquinones (CHEBI:132124)
D-2-hydroxyacid dehydrogenase (quinone) activity	RO:0000057	(2R)-2-hydroxy monocarboxylic acid anion (CHEBI:58314)
D-2-hydroxyacid dehydrogenase (quinone) activity	RO:0000057	2-oxo monocarboxylic acid anion (CHEBI:35179)

This term has no children.

EC: 1.1.5.10
MetaCyc: RXN-14931
RHEA: 11272