AmiGO 2: Term Details for "exon-exon junction subcomplex mago-y14" (GO:1990501)

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Term Information

Accession: GO:1990501
Name: exon-exon junction subcomplex mago-y14
Ontology: cellular_component
Synonyms: MGN-RBM8A complex, exon junction subcomplex MAGOH-Y14, mago-y14 complex
Alternate IDs: None
Definition: Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA. Source: PMID:12730685, GOC:bhm
Comment: An example of this is Mago in drome (P49028) in PMID:12730685 (inferred from direct assay).
History: See term history for GO:1990501 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to exon-exon junction subcomplex mago-y14 (excluding "regulates").; Link to all direct and indirect annotations to exon-exon junction subcomplex mago-y14 (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for exon-exon junction subcomplex mago-y14 (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0050789 regulation of biological process
GO:0009987 cellular process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0048519 negative regulation of biological process
GO:0050794 regulation of cellular process
UBERON:0000061 anatomical structure
GO:0065007 biological regulation
CL:0000000 cell
GO:0051641 cellular localization
GO:0005575 cellular_component
GO:0051234 establishment of localization
GO:0051179 localization
GO:0008152 metabolic process
GO:0048523 negative regulation of cellular process
GO:0044238 primary metabolic process
GO:0019222 regulation of metabolic process
GO:0009058 biosynthetic process
GO:0009056 catabolic process
GO:0110165 cellular anatomical structure
GO:0051649 establishment of localization in cell
GO:0005622 intracellular anatomical structure
GO:0043170 macromolecule metabolic process
GO:0009892 negative regulation of metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009889 regulation of biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0080090 regulation of primary metabolic process
GO:0006810 transport
GO:0046907 intracellular transport
GO:0009059 macromolecule biosynthetic process
GO:0009057 macromolecule catabolic process
GO:0033036 macromolecule localization
GO:0009890 negative regulation of biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0071705 nitrogen compound transport
GO:0090304 nucleic acid metabolic process
GO:0034655 nucleobase-containing compound catabolic process
GO:0043226 organelle
GO:0048518 positive regulation of biological process
GO:0009893 positive regulation of metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0003674 molecular_function
GO:0016071 mRNA metabolic process
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0051169 nuclear transport
GO:0141188 nucleic acid catabolic process
GO:0015931 nucleobase-containing compound transport
GO:0048522 positive regulation of cellular process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0045935 positive regulation of nucleobase-containing compound metabolic process
GO:0010468 regulation of gene expression
GO:0051252 regulation of RNA metabolic process
GO:0006403 RNA localization
GO:0051236 establishment of RNA localization
GO:0043231 intracellular membrane-bounded organelle
GO:0098772 molecular function regulator activity
GO:0006402 mRNA catabolic process
GO:0010629 negative regulation of gene expression
GO:0050657 nucleic acid transport
GO:0006913 nucleocytoplasmic transport
GO:0051254 positive regulation of RNA metabolic process
GO:0009894 regulation of catabolic process
GO:1903311 regulation of mRNA metabolic process
GO:0006401 RNA catabolic process
GO:0060590 ATPase regulator activity
GO:0140678 molecular function inhibitor activity
GO:0051168 nuclear export
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005634 nucleus
GO:0009896 positive regulation of catabolic process
GO:1903313 positive regulation of mRNA metabolic process
GO:0032991 protein-containing complex
GO:0061013 regulation of mRNA catabolic process
GO:0050658 RNA transport
GO:0042030 ATPase inhibitor activity
GO:0051028 mRNA transport
GO:0140513 nuclear protein-containing complex
GO:0061014 positive regulation of mRNA catabolic process
GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006405 RNA export from nucleus
GO:1903503 ATPase inhibitor complex
GO:0035145 exon-exon junction complex
GO:0006406 mRNA export from nucleus
GO:2000624 positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:1990501 exon-exon junction subcomplex mago-y14

Parents of exon-exon junction subcomplex mago-y14 (GO:1990501)

subject	relation	object
exon-exon junction subcomplex mago-y14	RO:0002216	mRNA export from nucleus (GO:0006406)
exon-exon junction subcomplex mago-y14	RO:0002216	positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000624)
exon-exon junction subcomplex mago-y14	is_a	ATPase inhibitor complex (GO:1903503)
exon-exon junction subcomplex mago-y14	RO:0002162	Eukaryota (NCBITaxon:2759)
exon-exon junction subcomplex mago-y14	is_a	exon-exon junction complex (GO:0035145)

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