AmiGO 2: Term Details for "C/EBP complex" (GO:1990647)

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Term Information

Accession: GO:1990647
Name: C/EBP complex
Ontology: cellular_component
Synonyms: C/EBP homodimer complex, C/EBP transcription factor complex, C/EBPalpha complex, C/EBPalpha homodimer complex, C/EBPbeta complex, C/EBPbeta homodimer complex
Alternate IDs: None
Definition: A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities. Source: GOC:PARL, PMID:8657121, GOC:pad, GOC:bhm
Comment: An example of this is Cebpa in rat (P05554) in PMID:8657121 (inferred from direct assay).
History: See term history for GO:1990647 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to C/EBP complex (excluding "regulates").; Link to all direct and indirect annotations to C/EBP complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for C/EBP complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
GO:0009987 cellular process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0050789 regulation of biological process
UBERON:0000061 anatomical structure
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0005575 cellular_component
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0048518 positive regulation of biological process
GO:0044238 primary metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0043226 organelle
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0048522 positive regulation of cellular process
GO:0009893 positive regulation of metabolic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0080090 regulation of primary metabolic process
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
GO:0009059 macromolecule biosynthetic process
GO:0043228 non-membrane-bounded organelle
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0009891 positive regulation of biosynthetic process
GO:0031325 positive regulation of cellular metabolic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0043232 intracellular non-membrane-bounded organelle
GO:0043227 membrane-bounded organelle
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0031328 positive regulation of cellular biosynthetic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0045935 positive regulation of nucleobase-containing compound metabolic process
GO:0032991 protein-containing complex
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0005694 chromosome
GO:0006351 DNA-templated transcription
GO:0043231 intracellular membrane-bounded organelle
GO:0003674 molecular_function
GO:0010557 positive regulation of macromolecule biosynthetic process
GO:0051254 positive regulation of RNA metabolic process
PR:000050567 protein-containing material entity
GO:0032993 protein-DNA complex
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:0140110 transcription regulator activity
GO:0000785 chromatin
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:1902680 positive regulation of RNA biosynthetic process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0140513 nuclear protein-containing complex
GO:0045893 positive regulation of DNA-templated transcription
GO:0005667 transcription regulator complex
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0090575 RNA polymerase II transcription regulator complex
GO:1990647 C/EBP complex

Parents of C/EBP complex (GO:1990647)

subject	relation	object
C/EBP complex	is_a	RNA polymerase II transcription regulator complex (GO:0090575)
C/EBP complex	RO:0002216	positive regulation of transcription by RNA polymerase II (GO:0045944)

This term has no children.