Term Information

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Accession
GO:1990931
Name
mRNA N6-methyladenosine dioxygenase activity
Ontology
molecular_function
Synonyms
mRNA N(6)-methyladenine demethylase, mRNA N(6)-methyladenosine dioxygenase activity, RNA N6-methyladenosine dioxygenase activity
Alternate IDs
None
Definition
Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde. Source: PMID:26458103, PMID:22002720
Comment
None
History
See term history for GO:1990931 at QuickGO
Chem. react.
has participant N(6)-methyladenosine 5'-monophosphate(1-) residue
has participant adenosine 5'-monophosphate(1-) residue
has participant carbon dioxide
has participant 2-oxoglutarate(2-)
has participant dioxygen
has participant formaldehyde
has participant succinate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:1990931 from QuickGO

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Parents of mRNA N6-methyladenosine dioxygenase activity (GO:1990931)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mRNA N6-methyladenosine dioxygenase activity [RO:0000057 relation] RO:0000057  N(6)-methyladenosine 5'-monophosphate(1-) residue (CHEBI:74449)
mRNA N6-methyladenosine dioxygenase activity [is_a relation] is_a  oxidative RNA demethylase activity (GO:0035515)
mRNA N6-methyladenosine dioxygenase activity [RO:0000057 relation] RO:0000057  adenosine 5'-monophosphate(1-) residue (CHEBI:74411)
mRNA N6-methyladenosine dioxygenase activity [RO:0000057 relation] RO:0000057  carbon dioxide (CHEBI:16526)
mRNA N6-methyladenosine dioxygenase activity [RO:0000057 relation] RO:0000057  2-oxoglutarate(2-) (CHEBI:16810)
mRNA N6-methyladenosine dioxygenase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
mRNA N6-methyladenosine dioxygenase activity [RO:0000057 relation] RO:0000057  formaldehyde (CHEBI:16842)
mRNA N6-methyladenosine dioxygenase activity [RO:0000057 relation] RO:0000057  succinate(2-) (CHEBI:30031)

This term has no children.

EC
1.14.11.53
RHEA
49520