Pediatric Adverse Events Terminology
Pediatric Adverse Events Terminology Mapped to MedDRA
Non-Neoplastic Skin Disorder
Toxic Epidermal Necrolysis
A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.
A systemic, serious, and life-threatening disorder characterized by erythematous and necrotic lesions in the skin and mucous membranes that are associated with bullous detachment of the epidermis. The epidermal and mucous membranes detachment leads to sepsis and may be fatal. The lesions appear throughout the body and occupy more than 30% of the body surfaces. It is a hypersensitivity reaction usually caused by drugs (e.g., sulfonamides, nonsteroidal anti-inflammatory drugs, anticonvulsants, and antiretroviral drugs).
C0014518
C79777
Disease or Syndrome
Drug-induced rapidly evolving cutaneous reaction resulting in areas of painful skin sloughing of greater than 30% body surface area.
Lyell Syndrome
Lyell's Syndrome
MedDRA
NICHD
TEN
Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis
Toxic epidermal necrolysis
Toxic epidermal necrolysis
Toxic_Epidermal_Necrolysis
NICHD Terminology