Disease_May_Have_Finding
Disease_May_Have_Associated_Disease
Disease_Mapped_To_Gene
Disease_May_Have_Molecular_Abnormality
CTRP Terminology
CTRP Disease Terminology
Hereditary Nonpolyposis Colorectal Cancer Syndrome
CPTAC Terminology
CPTAC Baseline Medical Forms Terminology
GDC Terminology
CPTAC Pancreatic Baseline Form
Comorbidity
Cellosaurus Disease Terminology
Risk Factor
EWS Authorized Value Terminology
EWS Medical History Table
Childhood Cancer Predisposition Study Terminology
CCPS Disease Terminology
GDC Value Terminology
OS Authorized Value Terminology
OS Medical History Table
EPCAM Gene
MSH2 Gene
MLH1 Gene
PMS1 Gene
PMS2 Gene
HL Medical History Table
HL Authorized Value Terminology
MSH6 Gene
Cellosaurus Terminology
High-Frequency Microsatellite Instability
Inactivating MSH6 Gene Mutation
PMS1 Gene Inactivation
Inactivating PMS2 Gene Mutation
Ovarian Carcinoma
Renal Pelvis Carcinoma
Endometrial Carcinoma
Small Intestinal Carcinoma
DNA Repair Disorder
Lower Gastrointestinal Hemorrhage
Medical History Reported Term
Lynch Syndrome
An autosomal dominant hereditary neoplastic syndrome characterized by the development of colorectal carcinoma and a high risk of developing endometrial carcinoma, gastric carcinoma, ovarian carcinoma, renal pelvis carcinoma, and small intestinal carcinoma. Patients often develop colorectal carcinomas at an early age (mean, 45 years). In the majority of the cases the lesions arise from the proximal colon. At the molecular level, high-frequency microsatellite instability is present.
C1333990
C8494
CCPS
CPTAC
CTRP
Cellosaurus
Disease or Syndrome
Familial Non-Polyposis Colon Cancer (hMSH2, hMLH1, hPMS1, hPMS2)
GDC
Hereditary Colorectal Endometrial Cancer Syndrome
Hereditary Defective Mismatch Repair Syndrome
Hereditary Non-Polyposis Colon Cancer (hMSH2, hMLH1, hPMS1, hPMS2)
Hereditary Nonpolyposis Colon Cancer (hMSH2, hMLH1, hPMS1, hPMS2)
Hereditary_Non-Polyposis_Colon_Cancer
Lynch Syndrome
Lynch Syndrome
Lynch Syndrome
Lynch Syndrome
Lynch syndrome
PCDC
Ureter Carcinoma
Gastric Intestinal-Type Adenocarcinoma