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Protein Ontology report - voltage-gated potassium channel subunit KCNA2
PR:000000810 - http://purl.obolibrary.org/obo/PR_000000810
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000810   
  PRO namevoltage-gated potassium channel subunit KCNA2 
  Synonyms
PRO-Short-label: EXACT:KCNA2
Other: EXACT:NGK1 | voltage-gated K(+) channel HuKIV | voltage-gated potassium channel HBK5 | voltage-gated potassium channel subunit Kv1.2
RELATED:MK2
  Definition"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA2 gene or a 1:1 ortholog thereof. The Kv1.2 channel is involved in maintaining membrane potential, modulating electrical excitability in neurons and muscle. It can coassemble with other Kv1 subunits." [PMID:16382104
  PRO Categorygene 
  ParentPR:000000709
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 11                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:539
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000810 voltage-gated potassium channel subunit KCNA2, KCNA2


organism-gene



PR:P16389 potassium voltage-gated channel subfamily A member 2 (human), hKCNA2


organism-sequence



PR:P16389-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (human), hKCNA2/iso:1

Yes

organism-modification



PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human), hKCNA2/iso:1/Phos:1

Yes

organism-modification



PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human), hKCNA2/iso:1/Phos:2

Yes

organism-sequence



PR:P16389-2 potassium voltage-gated channel subfamily A member 2 isoform h2 (human), hKCNA2/iso:h2


organism-gene



PR:P63141 potassium voltage-gated channel subfamily A member 2 (mouse), mKCNA2


organism-sequence



PR:P63141-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (mouse), mKCNA2/iso:1


organism-modification



PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse), mKCNA2/iso:1/Phos:2

Yes

organism-gene



PR:P63142 potassium voltage-gated channel subfamily A member 2 (rat), rKCNA2


organism-sequence



PR:P63142-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (rat), rKCNA2/iso:1

Yes

organism-modification



PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat), rKCNA2/iso:1/Phos:2

Yes

organism-gene



PR:Q8I4B0 potassium voltage-gated channel protein shk-1 (worm), KCNA2 (worm)


organism-sequence



PR:Q8I4B0-1 potassium voltage-gated channel protein shk-1 isoform c (worm), KCNA2/iso:c (worm)


organism-sequence



PR:Q8I4B0-2 potassium voltage-gated channel protein shk-1 isoform b (worm), KCNA2/iso:b (worm)


organism-sequence



PR:Q8I4B0-3 potassium voltage-gated channel protein shk-1 isoform d (worm), KCNA2/iso:d (worm)


organism-sequence



PR:Q8I4B0-4 potassium voltage-gated channel protein shk-1 isoform a (worm), KCNA2/iso:a (worm)


organism-sequence



PR:Q8I4B0-5 potassium voltage-gated channel protein shk-1 isoform e (worm), KCNA2/iso:e (worm)


organism-sequence



PR:Q8I4B0-6 potassium voltage-gated channel protein shk-1 isoform f (worm), KCNA2/iso:f (worm)


organism-sequence



PR:Q8I4B0-7 potassium voltage-gated channel protein shk-1 isoform g (worm), KCNA2/iso:g (worm)


sequence



PR:000000972 voltage-gated potassium channel subunit KCNA2 isoform 1, KCNA2/iso:1


organism-sequence



PR:P16389-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (human), hKCNA2/iso:1

Yes

organism-modification



PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human), hKCNA2/iso:1/Phos:1

Yes

organism-modification



PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human), hKCNA2/iso:1/Phos:2

Yes

organism-sequence



PR:P63141-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (mouse), mKCNA2/iso:1


organism-modification



PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse), mKCNA2/iso:1/Phos:2

Yes

organism-sequence



PR:P63142-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (rat), rKCNA2/iso:1

Yes

organism-modification



PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat), rKCNA2/iso:1/Phos:2

Yes

modification



PR:000000991 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form, KCNA2/iso:1/PhosRes+


modification



PR:000001000 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1, KCNA2/iso:1/Phos:1


organism-modification



PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human), hKCNA2/iso:1/Phos:1

Yes

modification



PR:000001001 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2, KCNA2/iso:1/Phos:2


organism-modification



PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse), mKCNA2/iso:1/Phos:2

Yes

organism-modification



PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat), rKCNA2/iso:1/Phos:2

Yes

organism-modification



PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human), hKCNA2/iso:1/Phos:2

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036584
hKCNA2/iso:1/Phos:1
UniProtKB:P16389-1, Tyr-132, MOD:00048
enablesNOT GO:0005251 delayed rectifier potassium channel activity PMID:15215309
located_inGO:0005768 endosome PMID:15215309
PR:000036585
mKCNA2/iso:1/Phos:2
UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046
located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:000036586
rKCNA2/iso:1/Phos:2
UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046
located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:000036587
hKCNA2/iso:1/Phos:2
UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046
located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:P16389-1
hKCNA2/iso:1
enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:1715584
located_inGO:0008076 voltage-gated potassium channel complex PMID:2251283
GO:0009986 cell surface PMID:15215309
PR:P63142-1
rKCNA2/iso:1
enablesGO:0005515 protein binding with PR:P78352 DLG4 PMID:17959782