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Protein Ontology report - D(2) dopamine receptor
PR:000001177 - http://purl.obolibrary.org/obo/PR_000001177
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001177   
  PRO nameD(2) dopamine receptor 
  Synonyms
PRO-Short-label: EXACT:DRD2
Other: EXACT:dopamine D2 receptor
  Definition"A D(2)-like dopamine receptor that is a translation product of the human DRD2 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001108
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence2                                                  Organism-Sequence 17                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:215
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001177 D(2) dopamine receptor, DRD2

organism-gene


PR:P14416 D(2) dopamine receptor (human), hDRD2

organism-sequence


PR:P14416-1 D(2) dopamine receptor isoform 1 (human), hDRD2/iso:1

organism-sequence


PR:P14416-2 D(2) dopamine receptor isoform 2 (human), hDRD2/iso:2

organism-sequence


PR:P14416-3 D(2) dopamine receptor isoform h3 (human), hDRD2/iso:h3

organism-gene


PR:P61168 D(2) dopamine receptor (mouse), mDRD2

organism-sequence


PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse), mDRD2/iso:1
Yes
organism-sequence


PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse), mDRD2/iso:2
Yes
organism-gene


PR:P61169 D(2) dopamine receptor (rat), rDRD2

organism-sequence


PR:P61169-1 D(2) dopamine receptor isoform Long (rat), rDRD2/iso:Long

organism-sequence


PR:P61169-2 D(2) dopamine receptor isoform Short (rat), rDRD2/iso:Short

organism-gene


PR:Q6RYS9 dopamine receptor 3 (worm), DRD2 (worm)

organism-sequence


PR:Q6RYS9-1 dopamine receptor 3 isoform b (worm), DRD2/iso:b (worm)

organism-sequence


PR:Q6RYS9-2 dopamine receptor 3 isoform a (worm), DRD2/iso:a (worm)

organism-sequence


PR:Q6RYS9-3 dopamine receptor 3 isoform c (worm), DRD2/iso:c (worm)

organism-sequence


PR:Q6RYS9-4 dopamine receptor 3 isoform d (worm), DRD2/iso:d (worm)

organism-gene


PR:Q8IS44 dopamine D2-like receptor (fruit fly), fly-DRD2

organism-sequence


PR:Q8IS44-1 dopamine D2-like receptor isoform H (fruit fly), fly-DRD2/iso:H

organism-sequence


PR:Q8IS44-2 dopamine D2-like receptor isoform J (fruit fly), fly-DRD2/iso:J

organism-sequence


PR:Q8IS44-3 dopamine D2-like receptor isoform F (fruit fly), fly-DRD2/iso:F

organism-sequence


PR:Q8IS44-4 dopamine D2-like receptor isoform B (fruit fly), fly-DRD2/iso:B

organism-sequence


PR:Q8IS44-5 dopamine D2-like receptor isoform G (fruit fly), fly-DRD2/iso:G

organism-sequence


PR:Q8IS44-6 dopamine D2-like receptor isoform I (fruit fly), fly-DRD2/iso:I

organism-gene


PR:Q9GJU1 D(2) dopamine receptor (dog), dog-DRD2

sequence


PR:000037412 D(2) dopamine receptor isoform 1, DRD2/iso:1

organism-sequence


PR:P14416-1 D(2) dopamine receptor isoform 1 (human), hDRD2/iso:1

organism-sequence


PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse), mDRD2/iso:1
Yes
sequence


PR:000037413 D(2) dopamine receptor isoform 2, DRD2/iso:2

organism-sequence


PR:P14416-2 D(2) dopamine receptor isoform 2 (human), hDRD2/iso:2

organism-sequence


PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse), mDRD2/iso:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P61168-1
mDRD2/iso:1
D2A (mouse)		 acts_upstream_of_or_withinGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway MGI:893272; PMID:7706278
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway MGI:893272; PMID:7706278
GO:0007212 dopamine receptor signaling pathway MGI:2181304; PMID:11089973
GO:0007626 locomotory behavior MGI:1927281; PMID:11069937
GO:0032228 regulation of synaptic transmission, GABAergic MGI:3628700; PMID:15489038
GO:0060134 prepulse inhibition MGI:3611062; PMID:12476322
enablesGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI:893272; PMID:7706278
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI:893272; PMID:7706278
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI:893272; PMID:7706278
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI:893272; PMID:7706278
located_inGO:0016020 membrane MGI:893272; PMID:7706278
PR:P61168-2
mDRD2/iso:2
D2B (mouse)		 acts_upstream_of_or_withinGO:0001975 response to amphetamine MGI:3611062; PMID:12476322
GO:0014059 regulation of dopamine secretion MGI:3655899; PMID:11943831
GO:0032228 regulation of synaptic transmission, GABAergic MGI:3628700; PMID:15489038
GO:0042220 response to cocaine MGI:3655899; PMID:11943831
GO:0043278 response to morphine MGI:3655899; PMID:11943831
GO:0051967 negative regulation of synaptic transmission, glutamatergic MGI:3628700; PMID:15489038
GO:0060160 negative regulation of dopamine receptor signaling pathway MGI:2181304; PMID:11089973
enablesGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI:892768; PMID:1991517
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI:892768; PMID:1991517