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Protein Ontology report - RING-box protein
PR:000000004 - http://purl.obolibrary.org/obo/PR_000000004
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000004   
  PRO nameRING-box protein 
  Definition"A protein that has a core domain composition consisting of a Zinc finger, C3HC4 type (RING finger)(Pfam:PF00097) domain." [PMID:11573242] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family2                                                  Organism-Family 1                                        
         Gene3                                                  Organism-Gene 19                                        
         Sequence4                                                  Organism-Sequence 11                                        
         Modification6                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF016237
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000000004 RING-box protein, RING-box protein
Yes
gene


PR:000000044 RING-box protein 2, RNF7
Yes
organism-gene


PR:Q9M9L0 anaphase-promoting complex subunit 11 (Arabidopsis thaliana), At-RNF7

organism-gene


PR:Q9UBF6 RING-box protein 2 (human), hRNF7

organism-sequence


PR:Q9UBF6-1 RING-box protein 2 isoform 1 (human), hRNF7/iso:1

organism-modification


PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human), hRNF7/iso:1/Phos:1
Yes
organism-sequence


PR:Q9UBF6-2 RING-box protein 2 isoform 2 (human), hRNF7/iso:2
Yes
organism-sequence


PR:Q9UBF6-3 RING-box protein 2 isoform h3 (human), hRNF7/iso:h3

organism-sequence


PR:Q9UBF6-4 RING-box protein 2 isoform h4 (human), hRNF7/iso:h4

organism-modification


PR:000049057 RING-box protein 2, initiator methionine removed form (human), hRNF7/InitMet-

organism-modification


PR:000068715 RING-box protein 2 methylated 1 (human), hRNF7/Me:1

organism-modification


PR:000071162 RING-box protein 2 methylated 2 (human), hRNF7/Me:2

sequence


PR:000000178 RING-box protein 2 isoform 1, RNF7/iso:1

organism-sequence


PR:Q9UBF6-1 RING-box protein 2 isoform 1 (human), hRNF7/iso:1

organism-modification


PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human), hRNF7/iso:1/Phos:1
Yes
organism-sequence


PR:Q9WTZ1-1 RING-box protein 2 isoform 1 (mouse), mRNF7/iso:1
Yes
modification


PR:000000396 RING-box protein 2 isoform 1 phosphorylated form, RNF7/iso:1/PhosRes+

modification


PR:000000511 RING-box protein 2 isoform 1 phosphorylated 1, RNF7/iso:1/Phos:1

organism-modification


PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human), hRNF7/iso:1/Phos:1
Yes
modification


PR:000026651 RING-box protein 2 isoform 1, initiator methionine removed form, RNF7/iso:1/InitMet-

sequence


PR:000000179 RING-box protein 2 isoform 2, RNF7/iso:2

organism-sequence


PR:Q9UBF6-2 RING-box protein 2 isoform 2 (human), hRNF7/iso:2
Yes
modification


PR:000018273 RING-box protein 2, initiator methionine removed form, RNF7/InitMet-

modification


PR:000026651 RING-box protein 2 isoform 1, initiator methionine removed form, RNF7/iso:1/InitMet-

organism-modification


PR:000049057 RING-box protein 2, initiator methionine removed form (human), hRNF7/InitMet-

gene


PR:000004014 anaphase-promoting complex subunit 11, ANAPC11

organism-gene


PR:D3ZXH8 protein Anapc11 (rat), rANAPC11

organism-gene


PR:Q08BH9 APC11 anaphase promoting complex subunit 11 homolog (zebrafish), z-ANAPC11

organism-gene


PR:Q20052 anaphase-promoting complex subunit 11 (worm), ANAPC11 (worm)

organism-gene


PR:Q54L48 anaphase-promoting complex subunit 11 (Dictyostelium discoideum), Dicty-ANAPC11

organism-gene


PR:Q7KA43 AT07979p1 (fruit fly), fly-ANAPC11

organism-gene


PR:Q9CPX9 anaphase-promoting complex subunit 11 (mouse), mANAPC11

organism-sequence


PR:Q9CPX9-1 anaphase-promoting complex subunit 11 isoform 1 (mouse), mANAPC11/iso:1

organism-gene


PR:Q9NYG5 anaphase-promoting complex subunit 11 (human), hANAPC11

Yes
organism-sequence


PR:Q9NYG5-1 anaphase-promoting complex subunit 11 isoform 1 (human), hANAPC11/iso:1

organism-sequence


PR:Q9NYG5-2 anaphase-promoting complex subunit 11 isoform h2 (human), hANAPC11/iso:h2

organism-modification


PR:000066861 anaphase-promoting complex subunit 11 methylated 1 (human), hANAPC11/Me:1

organism-gene


PR:Q9UT86 anaphase-promoting complex subunit 11 (Schizosaccharomyces pombe 972h-), Spom972h-ANAPC11

sequence


PR:000043658 anaphase-promoting complex subunit 11 isoform 1, ANAPC11/iso:1

organism-sequence


PR:Q9CPX9-1 anaphase-promoting complex subunit 11 isoform 1 (mouse), mANAPC11/iso:1

organism-sequence


PR:Q9NYG5-1 anaphase-promoting complex subunit 11 isoform 1 (human), hANAPC11/iso:1

family


PR:000027961 RING-box protein 1 related protein, fam:RBX1

gene


PR:000000043 E3 ubiquitin-protein ligase RBX1, RBX1
Yes
organism-gene


PR:O13959 RING-box protein pip1 (Schizosaccharomyces pombe 972h-), Spom972h-RBX1

organism-gene


PR:P62877 E3 ubiquitin-protein ligase RBX1 (human), hRBX1

organism-sequence


PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human), hRBX1/iso:1
Yes
organism-modification


PR:000026756 E3 ubiquitin-protein ligase RBX1, initiator methionine removed form (human), hRBX1/InitMet-

Yes
organism-modification


PR:000065210 E3 ubiquitin-protein ligase RBX1 methylated 1 (human), hRBX1/Me:1

organism-modification


PR:000065917 E3 ubiquitin-protein ligase RBX1 cysteinylated 1 (human), hRBX1/Cyst:1

organism-modification


PR:000068175 E3 ubiquitin-protein ligase RBX1 cysteinylated 2 (human), hRBX1/Cyst:2

organism-gene


PR:P62878 E3 ubiquitin-protein ligase RBX1 (mouse), mRBX1

organism-sequence


PR:P62878-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (mouse), mRBX1/iso:1

organism-gene


PR:Q08273 RING-box protein HRT1 (yeast), yRBX1

organism-gene


PR:Q23457 RING-box protein 1 (worm), RBX1 (worm)

organism-gene


PR:Q54K33 RING-box protein 1 (Dictyostelium discoideum), Dicty-RBX1

organism-gene


PR:Q9W5E1 RING-box protein 1A (fruit fly), fly-RBX1

sequence


PR:000000177 E3 ubiquitin-protein ligase RBX1 isoform 1, RBX1/iso:1

organism-sequence


PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human), hRBX1/iso:1
Yes
organism-sequence


PR:P62878-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (mouse), mRBX1/iso:1

modification


PR:000026660 E3 ubiquitin-protein ligase RBX1 isoform 1, initiator methionine removed form, RBX1/iso:1/InitMet-

modification


PR:000018272 E3 ubiquitin-protein ligase RBX1, initiator methionine removed form, RBX1/InitMet-

modification


PR:000026660 E3 ubiquitin-protein ligase RBX1 isoform 1, initiator methionine removed form, RBX1/iso:1/InitMet-

organism-modification


PR:000026756 E3 ubiquitin-protein ligase RBX1, initiator methionine removed form (human), hRBX1/InitMet-

Yes
organism-family


PR:000028456 RING-box protein 1 (Arabidopsis thaliana), At-RBX1[a/b]

Yes




PR:Q940X7 RING-box protein 1a (Arabidopsis thaliana),





PR:Q9M2B0 RING-box protein 1b (Arabidopsis thaliana),

organism-gene


PR:Q940X7 RING-box protein 1a (Arabidopsis thaliana), At-RBX1A

organism-sequence


PR:Q940X7-1 RING-box protein 1a isoform 1 (Arabidopsis thaliana), At-RBX1A/iso:1

organism-gene


PR:Q9M2B0 RING-box protein 1b (Arabidopsis thaliana), At-RBX1B

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forms found in complexes   

Component
 Complexes
PR:000026756 hRBX1/InitMet- PR:000026771 SCF beta-TrCP complex (human)
PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
PR:000028456 At-RBX1[a/b] PR:000028458 SCF(TIR1) complex (Arabidopsis thaliana)
PR:000028465 SCF(COI1) complex (Arabidopsis thaliana)
PR:Q9NYG5 hANAPC11 PR:000026433 anaphase-promoting complex (human)
PR:000026444 phosphorylated anaphase-promoting complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000004 RING-box protein

"A protein that has a core domain composition consisting of a Zinc finger, C3HC4 type (RING finger)(Pfam:PF00097) domain." [PMID:11573242]		 acts_upstream_of_or_withinGO:0016567 protein ubiquitination PIRSF:PIRSF016237
enablesGO:0004842 ubiquitin-protein transferase activity PIRSF:PIRSF016237
GO:0005515 protein binding PIRSF:PIRSF016237
PR:000000043 RBX1
RNF75 | ROC1 | E3 ubiquitin-protein transferase RBX1 | protein ZYP | rbx1 | regulator of cullins 1 | RING finger protein 75 | RING-box protein 1
"A RING-box protein 1 related protein that is a translation product of the human RBX1 gene or a 1:1 ortholog thereof." [PRO:CNA]		 acts_upstream_of_or_withinGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500724
located_inGO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500724
PR:000000044 RNF7
RBX2 | ROC2 | SAG | CKBBP1 | CKII beta-binding protein 1 | rbx2 | regulator of cullins 2 | RING finger protein 7 | sensitive to apoptosis gene protein
"A RING-box protein that is a translation product of the human RNF7 gene or a 1:1 ortholog thereof." [PRO:CNA]		 acts_upstream_of_or_withinGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500725
located_inGO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500725
PR:000036431 hRNF7/iso:1/Phos:1
UniProtKB:Q9UBF6-1, Thr-10, MOD:00047
"A RING-box protein 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q9UBF6-1, Thr-10, MOD:00047." [PMID:12748192, PRO:CNA]		 located_inGO:0005634 nucleus PMID:12748192
GO:0005737 cytoplasm PMID:12748192
PR:P62877-1 hRBX1/iso:1

"An E3 ubiquitin-protein ligase RBX1 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006511 ubiquitin-dependent protein catabolic process PMID:10230407
GO:0006606 protein import into nucleus PMID:11027288
GO:0045116 protein neddylation PMID:15966899
enablesGO:0005515 protein binding with PR:Q13616-1 PMID:11027288
GO:0005515 protein binding with PR:Q9EQW6 mOLIG2 PMID:11027288
located_inGO:0000151 ubiquitin ligase complex PMID:17217622
GO:0000151 ubiquitin ligase complex PMID:17217622
GO:0019005 SCF ubiquitin ligase complex PMID:15966899
GO:0031462 Cul2-RING ubiquitin ligase complex PMID:15966899
PR:Q9UBF6-2 hRNF7/iso:2
RING-box protein 2 isoform SAG-v (human)
"A RING-box protein 2 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UBF6]		 located_inNOT GO:0000151 ubiquitin ligase complex PMID:11506706
PR:Q9WTZ1-1 mRNF7/iso:1

"A RING-box protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]		 acts_upstream_of_or_withinGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress PMID:10082581
located_inGO:0005634 nucleus PMID:10082581
GO:0005737 cytoplasm PMID:10082581