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Protein Ontology report - chordin
PR:000000010 - http://purl.obolibrary.org/obo/PR_000000010
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000010   
  PRO namechordin 
  Synonyms
PRO-Short-label: EXACT:CHRD
Gene-based: RELATED:UNQ217/PRO243
  Definition"A protein that is a translation product of the human CHRD gene or a 1:1 ortholog thereof. Chordin regulates signaling by BMP pathway." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence4                                                  Organism-Sequence 7                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF002496
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000010 chordin, CHRD
Yes
organism-gene


PR:O57472 chordin (zebrafish), z-CHRD

organism-gene


PR:Q24025 dorsal-ventral patterning protein Sog (fruit fly), fly-CHRD

organism-gene


PR:Q63148 chordin (rat), rCHRD

organism-gene


PR:Q91713 chordin (frog), frog-CHRD

organism-sequence


PR:Q91713-1 chordin isoform 1 (frog), frog-CHRD/iso:1

organism-modification


PR:000036410 chordin isoform 1, signal peptide removed form (frog), frog-CHRD/iso:1/SigPep-
Yes
organism-gene


PR:Q9H2X0 chordin (human), hCHRD

organism-sequence


PR:Q9H2X0-1 chordin isoform 1 (human), hCHRD/iso:1
Yes
organism-sequence


PR:Q9H2X0-2 chordin isoform 2 (human), hCHRD/iso:2
Yes
organism-sequence


PR:Q9H2X0-3 chordin isoform h3 (human), hCHRD/iso:h3

organism-sequence


PR:Q9H2X0-4 chordin isoform 4 (human), hCHRD/iso:4
Yes
organism-sequence


PR:Q9H2X0-5 chordin isoform 5 (human), hCHRD/iso:5
Yes
organism-gene


PR:Q9Z0E2 chordin (mouse), mCHRD

organism-sequence


PR:Q9Z0E2-1 chordin isoform 1 (mouse), mCHRD/iso:1

organism-modification


PR:000036409 chordin isoform 1, signal peptide removed form (mouse), mCHRD/iso:1/SigPep-
Yes
organism-modification


PR:000036411 chordin isoform 1 cleaved 2 (mouse), mCHRD/iso:1/Clv:2
Yes
sequence


PR:000000086 chordin isoform 1, CHRD/iso:1

organism-sequence


PR:Q91713-1 chordin isoform 1 (frog), frog-CHRD/iso:1

organism-modification


PR:000036410 chordin isoform 1, signal peptide removed form (frog), frog-CHRD/iso:1/SigPep-
Yes
organism-sequence


PR:Q9H2X0-1 chordin isoform 1 (human), hCHRD/iso:1
Yes
organism-sequence


PR:Q9Z0E2-1 chordin isoform 1 (mouse), mCHRD/iso:1

organism-modification


PR:000036409 chordin isoform 1, signal peptide removed form (mouse), mCHRD/iso:1/SigPep-
Yes
organism-modification


PR:000036411 chordin isoform 1 cleaved 2 (mouse), mCHRD/iso:1/Clv:2
Yes
modification


PR:000000424 chordin isoform 1, signal peptide removed form, CHRD/iso:1/SigPep-

organism-modification


PR:000036409 chordin isoform 1, signal peptide removed form (mouse), mCHRD/iso:1/SigPep-
Yes
organism-modification


PR:000036410 chordin isoform 1, signal peptide removed form (frog), frog-CHRD/iso:1/SigPep-
Yes
modification


PR:000000425 chordin isoform 1 cleaved 2, CHRD/iso:1/Clv:2

organism-modification


PR:000036411 chordin isoform 1 cleaved 2 (mouse), mCHRD/iso:1/Clv:2
Yes
sequence


PR:000000087 chordin isoform 2, CHRD/iso:2

organism-sequence


PR:Q9H2X0-2 chordin isoform 2 (human), hCHRD/iso:2
Yes
sequence


PR:000000088 chordin isoform 4, CHRD/iso:4

organism-sequence


PR:Q9H2X0-4 chordin isoform 4 (human), hCHRD/iso:4
Yes
sequence


PR:000000089 chordin isoform 5, CHRD/iso:5

organism-sequence


PR:Q9H2X0-5 chordin isoform 5 (human), hCHRD/iso:5
Yes
modification


PR:000025419 chordin proteolytic cleavage product, CHRD/ClvPrd

modification


PR:000000425 chordin isoform 1 cleaved 2, CHRD/iso:1/Clv:2

organism-modification


PR:000036411 chordin isoform 1 cleaved 2 (mouse), mCHRD/iso:1/Clv:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000010 CHRD
UNQ217/PRO243
"A protein that is a translation product of the human CHRD gene or a 1:1 ortholog thereof. Chordin regulates signaling by BMP pathway." [PRO:CNA]		 acts_upstream_of_or_withinGO:0030510 regulation of BMP signaling pathway PIRSF:PIRSF002496
enablesGO:0005515 protein binding PIRSF:PIRSF002496
GO:0008201 heparin binding PIRSF:PIRSF002496
GO:0045545 syndecan binding PIRSF:PIRSF002496
PR:000036409 mCHRD/iso:1/SigPep-
UniProtKB:Q9Z0E2-1, 27-948 | PRO_0000005365
"A chordin isoform 1, signal peptide removed form in mouse. UniProtKB:Q9Z0E2-1, 27-948." [PMID:10479448, PMID:11784076, PMID:15381701, PMID:15780974, PRO:CNA]		 acts_upstream_of_or_withinGO:0001501 skeletal system development PMID:11784076
GO:0030514 negative regulation of BMP signaling pathway PMID:10479448; PMID:15780974
enablesGO:0005515 protein binding PMID:15381701
GO:0008201 heparin binding PMID:15381701
located_inGO:0005615 extracellular space PMID:15780974
PR:000036410 frog-CHRD/iso:1/SigPep-
UniProtKB:Q91713-1, 20-941 | PRO_0000005367
"A chordin isoform 1, signal peptide removed form in frog. UniProtKB:Q91713-1, 20-941." [PMID:8752213, PRO:CNA]		 located_inGO:0005615 extracellular space PMID:8752213
GO:0032991 protein-containing complex PMID:8752213
PR:000036411 mCHRD/iso:1/Clv:2
UniProtKB:Q9Z0E2-1, 154-861
"A chordin isoform 1 cleaved 2 in mouse. UniProtKB:Q9Z0E2-1, 154-861." [PMID:10479448, PRO:CNA]		 acts_upstream_of_or_withinGO:0001501 skeletal system development PMID:10479448
located_inGO:0005615 extracellular space PMID:10479448
PR:Q9H2X0-1 hCHRD/iso:1

"A chordin isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0001501 skeletal system development PMID:9782094
PR:Q9H2X0-2 hCHRD/iso:2

"A chordin isoform 2 that is encoded in the genome of human." [PRO:CNA, PRO:DNx]		 acts_upstream_of_or_withinNOT GO:0030514 negative regulation of BMP signaling pathway PMID:11472837
PR:Q9H2X0-4 hCHRD/iso:4

"A chordin isoform 4 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0030514 negative regulation of BMP signaling pathway PMID:11472837
PR:Q9H2X0-5 hCHRD/iso:5

"A chordin isoform 5 that is encoded in the genome of human." [PRO:CNA, PRO:DAN]		 acts_upstream_of_or_withinGO:0030514 negative regulation of BMP signaling pathway PMID:11472837