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Protein Ontology report - ribosomal protein S6 kinase beta
PR:000000025 - http://purl.obolibrary.org/obo/PR_000000025
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000025   
  PRO nameribosomal protein S6 kinase beta 
  Definition"A protein that specifically phosphorylates ribosomal protein S6 in response to insulin and other mitogens. It has a core domain composition consisting of a Protein kinase domain (Pfam:PF00069) followed by a Protein kinase C terminal domain (Pfam:PF00433)." [PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 7                                        
         Sequence3                                                  Organism-Sequence 12                                        
         Modification6                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF000605
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000000025 ribosomal protein S6 kinase beta, NOG
Yes
gene


PR:000000123 ribosomal protein S6 kinase beta-1, RPS6KB1

organism-gene


PR:P23443 ribosomal protein S6 kinase beta-1 (human), hRPS6KB1

organism-sequence


PR:P23443-1 ribosomal protein S6 kinase beta-1 isoform Alpha I (human), hRPS6KB1/iso:Alpha I
Yes
organism-modification


PR:000036480 ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 (human), hRPS6KB1/iso:1/Phos:1
Yes
organism-sequence


PR:P23443-2 ribosomal protein S6 kinase beta-1 isoform Alpha II (human), hRPS6KB1/iso:Alpha II
Yes
organism-modification


PR:000036481 ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human), hRPS6KB1/iso:2/Phos:1
Yes
organism-sequence


PR:P23443-3 ribosomal protein S6 kinase beta-1 isoform h2 (human), hRPS6KB1/iso:h2

organism-sequence


PR:P23443-4 ribosomal protein S6 kinase beta-1 isoform h3 (human), hRPS6KB1/iso:h3

organism-sequence


PR:P23443-5 ribosomal protein S6 kinase beta-1 isoform h4 (human), hRPS6KB1/iso:h4

organism-modification


PR:000049135 ribosomal protein S6 kinase beta-1 phosphorylated 2 (human), hRPS6KB1/Phos:2

organism-modification


PR:000069158 ribosomal protein S6 kinase beta-1 cysteinylated 1 (human), hRPS6KB1/Cyst:1

organism-modification


PR:000071099 ribosomal protein S6 kinase beta-1 phosphorylated 1 (human), hRPS6KB1/Phos:1

organism-modification


PR:000082924 ribosomal protein S6 kinase beta-1 cysteinylated 2 (human), hRPS6KB1/Cyst:2

organism-gene


PR:P67999 ribosomal protein S6 kinase beta-1 (rat), rRPS6KB1

organism-sequence


PR:P67999-1 ribosomal protein S6 kinase beta-1 isoform Alpha I (rat), rRPS6KB1/iso:Alpha I

organism-sequence


PR:P67999-2 ribosomal protein S6 kinase beta-1 isoform Alpha II (rat), rRPS6KB1/iso:Alpha II

organism-gene


PR:Q8BSK8 ribosomal protein S6 kinase beta-1 (mouse), mRPS6KB1

organism-sequence


PR:Q8BSK8-1 ribosomal protein S6 kinase beta-1 isoform Alpha I (mouse), mRPS6KB1/iso:Alpha I

organism-sequence


PR:Q8BSK8-2 ribosomal protein S6 kinase beta-1 isoform Alpha II (mouse), mRPS6KB1/iso:Alpha II

sequence


PR:000000310 ribosomal protein S6 kinase beta-1 isoform 1, RPS6KB1/iso:1

organism-sequence


PR:P23443-1 ribosomal protein S6 kinase beta-1 isoform Alpha I (human), hRPS6KB1/iso:Alpha I
Yes
organism-modification


PR:000036480 ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 (human), hRPS6KB1/iso:1/Phos:1
Yes
organism-sequence


PR:Q8BSK8-1 ribosomal protein S6 kinase beta-1 isoform Alpha I (mouse), mRPS6KB1/iso:Alpha I

modification


PR:000000463 ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated form, RPS6KB1/iso:1/PhosRes+

modification


PR:000000567 ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1, RPS6KB1/iso:1/Phos:1

organism-modification


PR:000036480 ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 (human), hRPS6KB1/iso:1/Phos:1
Yes
sequence


PR:000000311 ribosomal protein S6 kinase beta-1 isoform 2, RPS6KB1/iso:2

organism-sequence


PR:P23443-2 ribosomal protein S6 kinase beta-1 isoform Alpha II (human), hRPS6KB1/iso:Alpha II
Yes
organism-modification


PR:000036481 ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human), hRPS6KB1/iso:2/Phos:1
Yes
organism-sequence


PR:Q8BSK8-2 ribosomal protein S6 kinase beta-1 isoform Alpha II (mouse), mRPS6KB1/iso:Alpha II

modification


PR:000000464 ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated form, RPS6KB1/iso:2/PhosRes+

modification


PR:000000568 ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1, RPS6KB1/iso:2/Phos:1

organism-modification


PR:000036481 ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human), hRPS6KB1/iso:2/Phos:1
Yes
gene


PR:000000124 ribosomal protein S6 kinase beta-2, RPS6KB2

organism-gene


PR:Q8MYF1 probable serine/threonine-protein kinase DDB_G0277449 (Dictyostelium discoideum), Dicty-RPS6KB2

organism-gene


PR:Q9NAH6 ribosomal protein S6 kinase beta (worm), RPS6KB2 (worm)

organism-gene


PR:Q9UBS0 ribosomal protein S6 kinase beta-2 (human), hRPS6KB2

organism-sequence


PR:Q9UBS0-1 ribosomal protein S6 kinase beta-2 isoform 1 (human), hRPS6KB2/iso:1
Yes
organism-modification


PR:000026339 ribosomal protein S6 kinase beta-2 isoform 1 phosphorylated 1 (human), hRPS6KB2/iso:1/Phos:1

organism-sequence


PR:Q9UBS0-2 ribosomal protein S6 kinase beta-2 isoform h2 (human), hRPS6KB2/iso:h2

organism-modification


PR:000068932 ribosomal protein S6 kinase beta-2 phosphorylated 1 (human), hRPS6KB2/Phos:1

organism-modification


PR:000080961 ribosomal protein S6 kinase beta-2 phosphorylated 2 (human), hRPS6KB2/Phos:2

organism-gene


PR:Q9Z1M4 ribosomal protein S6 kinase beta-2 (mouse), mRPS6KB2

organism-sequence


PR:Q9Z1M4-1 ribosomal protein S6 kinase beta-2 isoform 1 (mouse), mRPS6KB2/iso:1
Yes
sequence


PR:000000312 ribosomal protein S6 kinase beta-2 isoform 1, RPS6KB2/iso:1

organism-sequence


PR:Q9UBS0-1 ribosomal protein S6 kinase beta-2 isoform 1 (human), hRPS6KB2/iso:1
Yes
organism-modification


PR:000026339 ribosomal protein S6 kinase beta-2 isoform 1 phosphorylated 1 (human), hRPS6KB2/iso:1/Phos:1

organism-sequence


PR:Q9Z1M4-1 ribosomal protein S6 kinase beta-2 isoform 1 (mouse), mRPS6KB2/iso:1
Yes
modification


PR:000000465 ribosomal protein S6 kinase beta-2 isoform 1 phosphorylated form, RPS6KB2/iso:1/PhosRes+

modification


PR:000000569 ribosomal protein S6 kinase beta-2 isoform 1 phosphorylated 1, RPS6KB2/iso:1/Phos:1

organism-modification


PR:000026339 ribosomal protein S6 kinase beta-2 isoform 1 phosphorylated 1 (human), hRPS6KB2/iso:1/Phos:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000025 NOG

"A protein that specifically phosphorylates ribosomal protein S6 in response to insulin and other mitogens. It has a core domain composition consisting of a Protein kinase domain (Pfam:PF00069) followed by a Protein kinase C terminal domain (Pfam:PF00433)." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006468 protein phosphorylation PANTHER:PTHR24351; PIRSF:PIRSF000605
enablesGO:0004672 protein kinase activity PANTHER:PTHR24351; PIRSF:PIRSF000605
GO:0004711 ribosomal protein S6 kinase activity PANTHER:PTHR24351; PIRSF:PIRSF000605
PR:000036480 hRPS6KB1/iso:1/Phos:1
UniProtKB:P23443-1, Ser-441/Ser-447, MOD:00046|Thr-444, MOD:00047
"A ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 in human. UniProtKB:P23443-1, Ser-441/Ser-447, MOD:00046|Thr-444, MOD:00047." [PMID:1922062, PRO:CNA]		 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:1922062
enablesGO:0004672 protein kinase activity PMID:1922062
PR:000036481 hRPS6KB1/iso:2/Phos:1

"A ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 in human." [PMID:1922062, PRO:CNA]		 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:1922062
enablesGO:0004672 protein kinase activity PMID:1922062
PR:P23443-1 hRPS6KB1/iso:Alpha I
ribosomal protein S6 kinase beta-1 isoform p80-S6K 1 (human)
"A ribosomal protein S6 kinase beta-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:1922062
enablesNOT GO:0004672 protein kinase activity PMID:1922062
PR:P23443-2 hRPS6KB1/iso:Alpha II

"A ribosomal protein S6 kinase beta-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:1922062
enablesNOT GO:0004672 protein kinase activity PMID:1922062
PR:Q9UBS0-1 hRPS6KB2/iso:1

"A ribosomal protein S6 kinase beta-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006412 translation PMID:9804755
GO:0007165 signal transduction PMID:9804755
PR:Q9Z1M4-1 mRPS6KB2/iso:1

"A ribosomal protein S6 kinase beta-2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]		 enablesGO:0004674 protein serine/threonine kinase activity PMID:15249583