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Protein Ontology report - DNA-binding protein inhibitor ID-3
PR:000000041 - http://purl.obolibrary.org/obo/PR_000000041
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000041   
  PRO nameDNA-binding protein inhibitor ID-3 
  Synonyms
PRO-Short-label: EXACT:ID3
Gene-based: RELATED:1R21 | BHLHB25 | HEIR1 | Hlh462 | Id-3 | Idb3
Other: EXACT:bHLHb25 | class B basic helix-loop-helix protein 25 | helix-loop-helix protein HEIR-1 | ID-like protein inhibitor HLH 1R21 | ID-like protein inhibitor HLH 462 | inhibitor of differentiation 3 | inhibitor of DNA binding 3
  Definition"An HLH DNA-binding protein inhibitor that is a translation product of the human ID3 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000003
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500479
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000041 DNA-binding protein inhibitor ID-3, ID3

Yes

organism-gene



PR:P41133 DNA-binding protein inhibitor ID-3 (mouse), mID3


organism-sequence



PR:P41133-1 DNA-binding protein inhibitor ID-3 isoform 1 (mouse), mID3/iso:1

Yes

organism-modification



PR:000036430 DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse), mID3/iso:1/Ubiq:1

Yes

organism-gene



PR:P41138 DNA-binding protein inhibitor ID-3 (rat), rID3


organism-gene



PR:Q02535 DNA-binding protein inhibitor ID-3 (human), hID3

Yes

organism-sequence



PR:Q02535-1 DNA-binding protein inhibitor ID-3 isoform 1 (human), hID3/iso:1

Yes

organism-modification



PR:000036429 DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human), hID3/iso:1/Phos:1

Yes

organism-modification



PR:000064894 DNA-binding protein inhibitor ID-3 methylated 1 (human), hID3/Me:1


organism-modification



PR:000068204 DNA-binding protein inhibitor ID-3 cysteinylated 1 (human), hID3/Cyst:1


organism-modification



PR:000073735 DNA-binding protein inhibitor ID-3 methylated 2 (human), hID3/Me:2


organism-modification



PR:000081463 DNA-binding protein inhibitor ID-3 cysteinylated 2 (human), hID3/Cyst:2


organism-modification



PR:000082453 DNA-binding protein inhibitor ID-3 phosphorylated 1 (human), hID3/Phos:1


sequence



PR:000000174 DNA-binding protein inhibitor ID-3 isoform 1, ID3/iso:1


organism-sequence



PR:P41133-1 DNA-binding protein inhibitor ID-3 isoform 1 (mouse), mID3/iso:1

Yes

organism-modification



PR:000036430 DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse), mID3/iso:1/Ubiq:1

Yes

organism-sequence



PR:Q02535-1 DNA-binding protein inhibitor ID-3 isoform 1 (human), hID3/iso:1

Yes

organism-modification



PR:000036429 DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human), hID3/iso:1/Phos:1

Yes

modification



PR:000000393 DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated form, ID3/iso:1/PhosRes+


modification



PR:000000508 DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1, ID3/iso:1/Phos:1


organism-modification



PR:000036429 DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human), hID3/iso:1/Phos:1

Yes

modification



PR:000000394 DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated form, ID3/iso:1/UbiqLys+


modification



PR:000000509 DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1, ID3/iso:1/Ubiq:1


organism-modification



PR:000036430 DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse), mID3/iso:1/Ubiq:1

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000041
ID3
1R21 | BHLHB25 | HEIR1 | Hlh462 | Id-3 | Idb3 | bHLHb25 | class B basic helix-loop-helix protein 25 | helix-loop-helix protein HEIR-1 | ID-like protein inhibitor HLH 1R21 | ID-like protein inhibitor HLH 462 | inhibitor of differentiation 3 | inhibitor of DNA binding 3
acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PIRSF:PIRSF500479
PR:000036429
hID3/iso:1/Phos:1
UniProtKB:Q02535-1, Ser-5, MOD:00046
acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:9372912
PR:000036430
mID3/iso:1/Ubiq:1
located_inGO:0005737 cytoplasm PMID:15451666
PR:P41133-1
mID3/iso:1
acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II PMID:2000388
located_inGO:0005634 nucleus PMID:15451666
PR:Q02535
hID3
1R21 | BHLHB25 | HEIR1 | ID3 | class B basic helix-loop-helix protein 25 (human) | helix-loop-helix protein HEIR-1 (human) | ID-like protein inhibitor HLH 1R21 (human) | inhibitor of differentiation 3 (human) | inhibitor of DNA binding 3 (human)
acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PMID:14627819
PR:Q02535-1
hID3/iso:1
acts_upstream_of_or_withinGO:0007275 multicellular organism development PMID:1628620
GO:0045892 negative regulation of DNA-templated transcription PMID:8437843
enablesGO:0003714 transcription corepressor activity PMID:8437843