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Protein Ontology report - E3 ubiquitin-protein ligase RBX1
PR:000000043 - http://purl.obolibrary.org/obo/PR_000000043
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000043   
  PRO nameE3 ubiquitin-protein ligase RBX1 
  Synonyms
PRO-Short-label: EXACT:RBX1
Gene-based: RELATED:RNF75 | ROC1
Other: EXACT:E3 ubiquitin-protein transferase RBX1 | protein ZYP | rbx1 | regulator of cullins 1 | RING finger protein 75 | RING-box protein 1
  Definition"A RING-box protein 1 related protein that is a translation product of the human RBX1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000027961 RING-box protein 1 related protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000043 E3 ubiquitin-protein ligase RBX1, RBX1
Yes
organism-gene


PR:O13959 RING-box protein pip1 (Schizosaccharomyces pombe 972h-), Spom972h-RBX1

organism-gene


PR:P62877 E3 ubiquitin-protein ligase RBX1 (human), hRBX1

organism-sequence


PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human), hRBX1/iso:1
Yes
organism-modification


PR:000026756 E3 ubiquitin-protein ligase RBX1, initiator methionine removed form (human), hRBX1/InitMet-

Yes
organism-modification


PR:000065210 E3 ubiquitin-protein ligase RBX1 methylated 1 (human), hRBX1/Me:1

organism-modification


PR:000065917 E3 ubiquitin-protein ligase RBX1 cysteinylated 1 (human), hRBX1/Cyst:1

organism-modification


PR:000068175 E3 ubiquitin-protein ligase RBX1 cysteinylated 2 (human), hRBX1/Cyst:2

organism-gene


PR:P62878 E3 ubiquitin-protein ligase RBX1 (mouse), mRBX1

organism-sequence


PR:P62878-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (mouse), mRBX1/iso:1

organism-gene


PR:Q08273 RING-box protein HRT1 (yeast), yRBX1

organism-gene


PR:Q23457 RING-box protein 1 (worm), RBX1 (worm)

organism-gene


PR:Q54K33 RING-box protein 1 (Dictyostelium discoideum), Dicty-RBX1

organism-gene


PR:Q9W5E1 RING-box protein 1A (fruit fly), fly-RBX1

sequence


PR:000000177 E3 ubiquitin-protein ligase RBX1 isoform 1, RBX1/iso:1

organism-sequence


PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human), hRBX1/iso:1
Yes
organism-sequence


PR:P62878-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (mouse), mRBX1/iso:1

modification


PR:000026660 E3 ubiquitin-protein ligase RBX1 isoform 1, initiator methionine removed form, RBX1/iso:1/InitMet-

modification


PR:000018272 E3 ubiquitin-protein ligase RBX1, initiator methionine removed form, RBX1/InitMet-

modification


PR:000026660 E3 ubiquitin-protein ligase RBX1 isoform 1, initiator methionine removed form, RBX1/iso:1/InitMet-

organism-modification


PR:000026756 E3 ubiquitin-protein ligase RBX1, initiator methionine removed form (human), hRBX1/InitMet-

Yes
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RBX1 forms found in complexes   

RBX1 Component
 Complexes
PR:000026756 hRBX1/InitMet- PR:000026771 SCF beta-TrCP complex (human)
PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000043 RBX1
RNF75 | ROC1 | E3 ubiquitin-protein transferase RBX1 | protein ZYP | rbx1 | regulator of cullins 1 | RING finger protein 75 | RING-box protein 1
"A RING-box protein 1 related protein that is a translation product of the human RBX1 gene or a 1:1 ortholog thereof." [PRO:CNA]		 acts_upstream_of_or_withinGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500724
located_inGO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500724
PR:P62877-1 hRBX1/iso:1

"An E3 ubiquitin-protein ligase RBX1 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006511 ubiquitin-dependent protein catabolic process PMID:10230407
GO:0006606 protein import into nucleus PMID:11027288
GO:0045116 protein neddylation PMID:15966899
enablesGO:0005515 protein binding with PR:Q13616-1 PMID:11027288
GO:0005515 protein binding with PR:Q9EQW6 mOLIG2 PMID:11027288
located_inGO:0000151 ubiquitin ligase complex PMID:17217622
GO:0000151 ubiquitin ligase complex PMID:17217622
GO:0019005 SCF ubiquitin ligase complex PMID:15966899
GO:0031462 Cul2-RING ubiquitin ligase complex PMID:15966899