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Protein Ontology report - RING-box protein 2
PR:000000044 - http://purl.obolibrary.org/obo/PR_000000044
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000044   
  PRO nameRING-box protein 2 
  Synonyms
PRO-Short-label: EXACT:RNF7
Gene-based: RELATED:RBX2 | ROC2 | SAG
Other: EXACT:CKBBP1 | CKII beta-binding protein 1 | rbx2 | regulator of cullins 2 | RING finger protein 7 | sensitive to apoptosis gene protein
  Definition"A RING-box protein that is a translation product of the human RNF7 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000004 RING-box protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 5                                        
         Modification4                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500725
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000044 RING-box protein 2, RNF7
Yes
organism-gene


PR:Q9M9L0 anaphase-promoting complex subunit 11 (Arabidopsis thaliana), At-RNF7

organism-gene


PR:Q9UBF6 RING-box protein 2 (human), hRNF7

organism-sequence


PR:Q9UBF6-1 RING-box protein 2 isoform 1 (human), hRNF7/iso:1

organism-modification


PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human), hRNF7/iso:1/Phos:1
Yes
organism-sequence


PR:Q9UBF6-2 RING-box protein 2 isoform 2 (human), hRNF7/iso:2
Yes
organism-sequence


PR:Q9UBF6-3 RING-box protein 2 isoform h3 (human), hRNF7/iso:h3

organism-sequence


PR:Q9UBF6-4 RING-box protein 2 isoform h4 (human), hRNF7/iso:h4

organism-modification


PR:000049057 RING-box protein 2, initiator methionine removed form (human), hRNF7/InitMet-

organism-modification


PR:000068715 RING-box protein 2 methylated 1 (human), hRNF7/Me:1

organism-modification


PR:000071162 RING-box protein 2 methylated 2 (human), hRNF7/Me:2

sequence


PR:000000178 RING-box protein 2 isoform 1, RNF7/iso:1

organism-sequence


PR:Q9UBF6-1 RING-box protein 2 isoform 1 (human), hRNF7/iso:1

organism-modification


PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human), hRNF7/iso:1/Phos:1
Yes
organism-sequence


PR:Q9WTZ1-1 RING-box protein 2 isoform 1 (mouse), mRNF7/iso:1
Yes
modification


PR:000000396 RING-box protein 2 isoform 1 phosphorylated form, RNF7/iso:1/PhosRes+

modification


PR:000000511 RING-box protein 2 isoform 1 phosphorylated 1, RNF7/iso:1/Phos:1

organism-modification


PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human), hRNF7/iso:1/Phos:1
Yes
modification


PR:000026651 RING-box protein 2 isoform 1, initiator methionine removed form, RNF7/iso:1/InitMet-

sequence


PR:000000179 RING-box protein 2 isoform 2, RNF7/iso:2

organism-sequence


PR:Q9UBF6-2 RING-box protein 2 isoform 2 (human), hRNF7/iso:2
Yes
modification


PR:000018273 RING-box protein 2, initiator methionine removed form, RNF7/InitMet-

modification


PR:000026651 RING-box protein 2 isoform 1, initiator methionine removed form, RNF7/iso:1/InitMet-

organism-modification


PR:000049057 RING-box protein 2, initiator methionine removed form (human), hRNF7/InitMet-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000044 RNF7
RBX2 | ROC2 | SAG | CKBBP1 | CKII beta-binding protein 1 | rbx2 | regulator of cullins 2 | RING finger protein 7 | sensitive to apoptosis gene protein
"A RING-box protein that is a translation product of the human RNF7 gene or a 1:1 ortholog thereof." [PRO:CNA]		 acts_upstream_of_or_withinGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500725
located_inGO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500725
PR:000036431 hRNF7/iso:1/Phos:1
UniProtKB:Q9UBF6-1, Thr-10, MOD:00047
"A RING-box protein 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q9UBF6-1, Thr-10, MOD:00047." [PMID:12748192, PRO:CNA]		 located_inGO:0005634 nucleus PMID:12748192
GO:0005737 cytoplasm PMID:12748192
PR:Q9UBF6-2 hRNF7/iso:2
RING-box protein 2 isoform SAG-v (human)
"A RING-box protein 2 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UBF6]		 located_inNOT GO:0000151 ubiquitin ligase complex PMID:11506706
PR:Q9WTZ1-1 mRNF7/iso:1

"A RING-box protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]		 acts_upstream_of_or_withinGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress PMID:10082581
located_inGO:0005634 nucleus PMID:10082581
GO:0005737 cytoplasm PMID:10082581