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Protein Ontology report - TGF-beta receptor type-2 isoform RII-2
PR:000000049 - http://purl.obolibrary.org/obo/PR_000000049
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000049   
  PRO nameTGF-beta receptor type-2 isoform RII-2 
  Synonyms
PRO-Short-label: EXACT:TGFBR2/iso:RII-2
Other: EXACT:TGF-beta receptor isoform 2 | TGFBR2 isoform 2
  Definition"A TGF-beta receptor type-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62312-1 or a 1:1 ortholog thereof." [PMID:7957954, PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000005 TGF-beta receptor type-2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000049 TGF-beta receptor type-2 isoform RII-2, TGFBR2/iso:RII-2

organism-sequence


PR:P37173-2 TGF-beta receptor type-2 isoform RII-2 (human), hTGFBR2/iso:RII-2
Yes
organism-sequence


PR:Q62312-1 TGF-beta receptor type-2 isoform RII-2 (mouse), mTGFBR2/iso:RII-2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P37173-2 hTGFBR2/iso:RII-2
TGF-beta receptor type-2 isoform 2 (human) | TGFBR2 isoform 2 (human)
"A TGF-beta receptor type-2 isoform RII-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P37173]		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:7959019; PMID:8635485
GO:0008284 positive regulation of cell population proliferation PMID:7959019
enablesGO:0005026 transforming growth factor beta receptor activity, type II PMID:7959019; PMID:8635485
GO:0050431 transforming growth factor beta binding PMID:8635485
PR:Q62312-1 mTGFBR2/iso:RII-2

"A TGF-beta receptor type-2 isoform RII-2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q62312]		 enablesGO:0050431 transforming growth factor beta binding PMID:7957954
located_inGO:0016020 membrane PMID:7959019