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Protein Ontology report - TGF-beta receptor type-2 sequence variant V387M (human)
PR:000000061 -
http://purl.obolibrary.org/obo/PR_000000061
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000000061
PRO name
TGF-beta receptor type-2 sequence variant V387M (human)
Synonyms
PRO-Short-label
:
EXACT:
hTGFBR2/var:V387M
PRO-proteoform-std
:
EXACT:
UniProtKB:P37173
, Val-387,
CHEBI:16044
NARROW:
UniProtKB:P37173-1
, Val-387,
CHEBI:16044
Other
:
EXACT:
TGF-beta receptor type-2 sequence variant 5 (human)
Definition
"A TGF-beta receptor type-2 (human) that has a Met residue at the position equivalent to Val-387 of the amino acid sequence represented by
UniProtKB:P37173-1
. Example:
UniProtKB:P37173-1
, Val-387,
CHEBI:16044
." [
PMID:11212236
, PRO:CNA, PRO:DAN]
PRO Category
organism-sequence
Parent
PR:P37173
TGF-beta receptor type-2 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB_VAR:VAR_022355
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000000061
hTGFBR2/var:V387M
UniProtKB:P37173, Val-387, CHEBI:16044 | UniProtKB:P37173-1, Val-387, CHEBI:16044 | TGF-beta receptor type-2 sequence variant 5 (human)
"A TGF-beta receptor type-2 (human) that has a Met residue at the position equivalent to Val-387 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Val-387, CHEBI:16044." [PMID:11212236, PRO:CNA, PRO:DAN]
acts_upstream_of_or_within
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:11212236
enables
decreased
GO:0005026
transforming growth factor beta receptor activity, type II
relative to
PR:000000409
TGF-beta receptor type-2 isoform 1 cleaved 1
PMID:11212236
located_in
GO:0016020
membrane
PMID:11212236