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Protein Ontology report - chordin isoform 1

PR:000000086 - http://purl.obolibrary.org/obo/PR_000000086

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000000086

PRO name

chordin isoform 1

Synonyms

PRO-Short-label:

EXACT:

CHRD/iso:1

Definition

"A chordin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-1 or a 1:1 ortholog thereof." [PMID:10479448, PRO:CNA, PRO:DAN]

PRO Category

sequence

Parent

PR:000000010

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Sequence	1	Organism-Sequence	3
Modification	2	Organism-Modification	3

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

sequence

PR:000000086 chordin isoform 1, CHRD/iso:1

organism-sequence

PR:Q91713-1 chordin isoform 1 (frog), frog-CHRD/iso:1

organism-modification

PR:000036410 chordin isoform 1, signal peptide removed form (frog), frog-CHRD/iso:1/SigPep-

Yes

organism-sequence

PR:Q9H2X0-1 chordin isoform 1 (human), hCHRD/iso:1

Yes

organism-sequence

PR:Q9Z0E2-1 chordin isoform 1 (mouse), mCHRD/iso:1

organism-modification

PR:000036409 chordin isoform 1, signal peptide removed form (mouse), mCHRD/iso:1/SigPep-

Yes

organism-modification

PR:000036411 chordin isoform 1 cleaved 2 (mouse), mCHRD/iso:1/Clv:2

Yes

modification

PR:000000424 chordin isoform 1, signal peptide removed form, CHRD/iso:1/SigPep-

organism-modification

PR:000036409 chordin isoform 1, signal peptide removed form (mouse), mCHRD/iso:1/SigPep-

Yes

organism-modification

PR:000036410 chordin isoform 1, signal peptide removed form (frog), frog-CHRD/iso:1/SigPep-

Yes

modification

PR:000000425 chordin isoform 1 cleaved 2, CHRD/iso:1/Clv:2

organism-modification

PR:000036411 chordin isoform 1 cleaved 2 (mouse), mCHRD/iso:1/Clv:2

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036409 mCHRD/iso:1/SigPep- UniProtKB:Q9Z0E2-1, 27-948 \| PRO_0000005365	acts_upstream_of_or_within	GO:0001501 skeletal system development	PMID:11784076
	acts_upstream_of_or_within	GO:0030514 negative regulation of BMP signaling pathway	PMID:10479448; PMID:15780974
	enables	GO:0005515 protein binding	PMID:15381701
	enables	GO:0008201 heparin binding	PMID:15381701
	located_in	GO:0005615 extracellular space	PMID:15780974
PR:000036410 frog-CHRD/iso:1/SigPep- UniProtKB:Q91713-1, 20-941 \| PRO_0000005367	located_in	GO:0005615 extracellular space	PMID:8752213
	located_in	GO:0032991 protein-containing complex	PMID:8752213
PR:000036411 mCHRD/iso:1/Clv:2 UniProtKB:Q9Z0E2-1, 154-861	acts_upstream_of_or_within	GO:0001501 skeletal system development	PMID:10479448
PR:000036411 mCHRD/iso:1/Clv:2 UniProtKB:Q9Z0E2-1, 154-861	located_in	GO:0005615 extracellular space	PMID:10479448
PR:Q9H2X0-1 hCHRD/iso:1	acts_upstream_of_or_within	GO:0001501 skeletal system development	PMID:9782094