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Protein Ontology report - TGF-beta 3

PR:000000184 - http://purl.obolibrary.org/obo/PR_000000184

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000000184

PRO name

TGF-beta 3

Synonyms

PRO-Short-label:	EXACT:	TGFB3
Other:	EXACT:	TGF-beta-3

Definition

"A TGF-beta that is a translation product of the human TGFB3 gene or a 1:1 ortholog thereof." [PRO:CNA]

PRO Category

gene

Parent

PR:000000046

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	1	Organism-Gene	4
Sequence	1	Organism-Sequence	3
Modification	5	Organism-Modification	3

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

gene

PR:000000184 TGF-beta 3, TGFB3

organism-gene

PR:P10600 transforming growth factor beta-3 (human), hTGFB3

organism-sequence

PR:P10600-1 transforming growth factor beta-3 isoform 1 (human), hTGFB3/iso:1

Yes

organism-modification

PR:000036536 TGF-beta 3 isoform 1 cleaved 1 (human), hTGFB3/iso:1/Clv:1

Yes

organism-sequence

PR:P10600-2 transforming growth factor beta-3 isoform h2 (human), hTGFB3/iso:h2

organism-gene

PR:P16047 transforming growth factor beta-3 proprotein (chicken), chick-TGFB3

organism-gene

PR:P17125 transforming growth factor beta-3 (mouse), mTGFB3

organism-sequence

PR:P17125-1 transforming growth factor beta-3 isoform 1 (mouse), mTGFB3/iso:1

Yes

organism-modification

PR:000036537 TGF-beta 3 isoform 1 cleaved 1 (mouse), mTGFB3/iso:1/Clv:1

Yes

organism-modification

PR:000036538 TGF-beta 3 isoform 1 cleaved 3 (mouse), mTGFB3/iso:1/Clv:3

Yes

organism-gene

PR:Q07258 transforming growth factor beta-3 proprotein (rat), rTGFB3

sequence

PR:000000406 TGF-beta 3 isoform 1, TGFB3/iso:1

organism-sequence

PR:P10600-1 transforming growth factor beta-3 isoform 1 (human), hTGFB3/iso:1

Yes

organism-modification

PR:000036536 TGF-beta 3 isoform 1 cleaved 1 (human), hTGFB3/iso:1/Clv:1

Yes

organism-sequence

PR:P17125-1 transforming growth factor beta-3 isoform 1 (mouse), mTGFB3/iso:1

Yes

organism-modification

PR:000036537 TGF-beta 3 isoform 1 cleaved 1 (mouse), mTGFB3/iso:1/Clv:1

Yes

organism-modification

PR:000036538 TGF-beta 3 isoform 1 cleaved 3 (mouse), mTGFB3/iso:1/Clv:3

Yes

modification

PR:000000634 TGF-beta 3 isoform 1 cleaved 1, TGFB3/iso:1/Clv:1

organism-modification

PR:000036536 TGF-beta 3 isoform 1 cleaved 1 (human), hTGFB3/iso:1/Clv:1

Yes

organism-modification

PR:000036537 TGF-beta 3 isoform 1 cleaved 1 (mouse), mTGFB3/iso:1/Clv:1

Yes

modification

PR:000021910 TGF-beta 3 isoform 1, signal peptide removed form, TGFB3/iso:1/SigPep-

modification

PR:000000635 TGF-beta 3 isoform 1 cleaved 2, TGFB3/iso:1/Clv:2

modification

PR:000000636 TGF-beta 3 isoform 1 cleaved 3, TGFB3/iso:1/Clv:3

organism-modification

PR:000036538 TGF-beta 3 isoform 1 cleaved 3 (mouse), mTGFB3/iso:1/Clv:3

Yes

modification

PR:000018294 TGF-beta 3 proteolytic cleavage product, TGFB3/ClvPrd

modification

PR:000000634 TGF-beta 3 isoform 1 cleaved 1, TGFB3/iso:1/Clv:1

organism-modification

PR:000036536 TGF-beta 3 isoform 1 cleaved 1 (human), hTGFB3/iso:1/Clv:1

Yes

organism-modification

PR:000036537 TGF-beta 3 isoform 1 cleaved 1 (mouse), mTGFB3/iso:1/Clv:1

Yes

modification

PR:000000635 TGF-beta 3 isoform 1 cleaved 2, TGFB3/iso:1/Clv:2

modification

PR:000000636 TGF-beta 3 isoform 1 cleaved 3, TGFB3/iso:1/Clv:3

organism-modification

PR:000036538 TGF-beta 3 isoform 1 cleaved 3 (mouse), mTGFB3/iso:1/Clv:3

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036536 hTGFB3/iso:1/Clv:1 UniProtKB:P10600-1, 301-412 \| PRO_0000033797	enables	GO:0005160 transforming growth factor beta receptor binding	PMID:18243111
	enables	GO:0042803 protein homodimerization activity	PMID:18243111
PR:000036537 mTGFB3/iso:1/Clv:1 UniProtKB:P17125-1, 299-410 \| PRO_0000033799	acts_upstream_of_or_within	GO:0030879 mammary gland development	PMID:1821856
PR:000036538 mTGFB3/iso:1/Clv:3 UniProtKB:P17125-1, 30-298, 299-410	acts_upstream_of_or_within	GO:0030879 mammary gland development	PMID:1821856
PR:P10600-1 hTGFB3/iso:1	acts_upstream_of_or_within	GO:0007165 signal transduction	PMID:3164476
PR:P10600-1 hTGFB3/iso:1	acts_upstream_of_or_within	GO:0007267 cell-cell signaling	PMID:3164476
PR:P17125-1 mTGFB3/iso:1	acts_upstream_of_or_within	GO:0030879 mammary gland development	PMID:1821856