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Protein Ontology report - activin receptor type-2B isoform ActR-IIB2
PR:000000209 - http://purl.obolibrary.org/obo/PR_000000209
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000209   
  PRO nameactivin receptor type-2B isoform ActR-IIB2 
  Synonyms
PRO-Short-label: EXACT:ACVR2B/iso:ActR-IIB2
Other: EXACT:activin receptor type-2B isoform 1 | ACVR2B isoform 1
  Definition"An activin receptor type-2B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27040-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  CommentNote: This isoform lacks the intracellular segment rich in basic and acidic residues (known as splicing cassette II). 
  PRO Categorysequence 
  ParentPR:000000071 activin receptor type-2B
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 3                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000209 activin receptor type-2B isoform ActR-IIB2, ACVR2B/iso:ActR-IIB2

organism-sequence


PR:P27040-2 activin receptor type-2B isoform ActR-IIB2 (mouse), mACVR2B/iso:ActR-IIB2

organism-modification


PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse), mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
organism-sequence


PR:Q13705-1 activin receptor type-2B isoform ActR-IIB2 (human), hACVR2B/iso:ActR-IIB2
Yes
organism-modification


PR:000036443 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human), hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
organism-sequence


PR:Q90670-1 activin receptor type-2B isoform ActR-IIB2 (chicken), chick-ACVR2B/iso:ActR-IIB2

modification


PR:000000415 activin receptor type-2B isoform ActR-IIB2 glycosylated and phosphorylated form, ACVR2B/iso:ActR-IIB2/GlycoPhos+

modification


PR:000000529 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1, ACVR2B/iso:ActR-IIB2/NGlycoPhos:1

organism-modification


PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse), mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
organism-modification


PR:000036443 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human), hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036442 mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse) | mACVR2B/iso:1/GlycoPhos:1
"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:1326537, PMID:16991118, PMID:8721982, PRO:CNA]		 acts_upstream_of_or_withinGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:8721982
GO:0009952 anterior/posterior pattern specification PMID:10452853; PMID:16991118
GO:0032925 regulation of activin receptor signaling pathway PMID:8721982
enablesGO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:1326537
GO:0019838 growth factor binding PMID:11459935; PMID:12414726
NOT GO:0050431 transforming growth factor beta binding PMID:1326537
PR:000036443 hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (human) | hACVR2B/iso:1/GlycoPhos:1
"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in human." [PMID:11279102, PMID:24337809, PMID:8161782, PMID:8622651, PMID:9872992, PRO:CNA, PRO:DAN]		 enablesGO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8622651
GO:0005515 protein binding PMID:11279102; PMID:9872992
GO:0016362 activin receptor activity, type II PMID:8622651
located_inGO:0005886 plasma membrane PMID:8161782
GO:0048179 activin receptor complex PMID:8622651
PR:Q13705-1 hACVR2B/iso:ActR-IIB2

"An activin receptor type-2B isoform ActR-IIB2 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:8161782