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Protein Ontology report - bone morphogenetic protein 2 isoform 1
PR:000000385 -
http://purl.obolibrary.org/obo/PR_000000385
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000385
PRO name
bone morphogenetic protein 2 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
BMP2/iso:1
Definition
"A bone morphogenetic protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P12643-1
or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000164
bone morphogenetic protein 2
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
2
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000000385
bone morphogenetic protein 2 isoform 1, BMP2/iso:1
organism-sequence
PR:P12643-1
bone morphogenetic protein 2 isoform 1 (human), hBMP2/iso:1
Yes
organism-modification
PR:000026336
bone morphogenetic protein 2 isoform 1, mature form (human), hBMP2/iso:1/mature
Yes
organism-sequence
PR:P21274-1
bone morphogenetic protein 2 isoform 1 (mouse), mBMP2/iso:1
Yes
organism-modification
PR:000036510
bone morphogenetic protein 2 isoform 1, mature form (mouse), mBMP2/iso:1/mature
Yes
modification
PR:000000608
bone morphogenetic protein 2 isoform 1, mature form, BMP2/iso:1/mature
organism-modification
PR:000026336
bone morphogenetic protein 2 isoform 1, mature form (human), hBMP2/iso:1/mature
Yes
organism-modification
PR:000036510
bone morphogenetic protein 2 isoform 1, mature form (mouse), mBMP2/iso:1/mature
Yes
modification
PR:000021898
bone morphogenetic protein 2 isoform 1, signal peptide removed form, BMP2/iso:1/SigPep-
modification
PR:000000608
bone morphogenetic protein 2 isoform 1, mature form, BMP2/iso:1/mature
organism-modification
PR:000026336
bone morphogenetic protein 2 isoform 1, mature form (human), hBMP2/iso:1/mature
Yes
organism-modification
PR:000036510
bone morphogenetic protein 2 isoform 1, mature form (mouse), mBMP2/iso:1/mature
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000026336
hBMP2/iso:1/mature
UniProtKB:P12643-1, 283-396 | PRO_0000033825
"A bone morphogenetic protein 2 isoform 1, mature form in human. UniProtKB:P12643-1, 283-396." [PRO:DNx, UniProtKB:P12643]
acts_upstream_of_or_within
GO:0001501
skeletal system development
PMID:2315314
GO:0007267
cell-cell signaling
PMID:2315314
enables
GO:0005102
signaling receptor binding
PMID:2315314
GO:0042803
protein homodimerization activity
PMID:10074410
located_in
GO:0005615
extracellular space
PMID:2315314
PR:000036510
mBMP2/iso:1/mature
UniProtKB:P21274-1, 281-394 | PRO_0000033827
"A bone morphogenetic protein 2 isoform 1, mature form in mouse. UniProtKB:P21274-1, 281-394." [PMID:14623234, PMID:15110716, PMID:15565649, PMID:16109715, PRO:CNA]
acts_upstream_of_or_within
GO:0001501
skeletal system development
PMID:15565649
;
PMID:16109715
GO:0030509
BMP signaling pathway
PMID:14623234
located_in
GO:0005615
extracellular space
PMID:15110716
PR:P12643-1
hBMP2/iso:1
"A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
acts_upstream_of_or_within
GO:0001501
skeletal system development
PMID:2315314
GO:0007267
cell-cell signaling
PMID:2315314
PR:P21274-1
mBMP2/iso:1
"A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
acts_upstream_of_or_within
GO:0030509
BMP signaling pathway
PMID:14623234