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RACE-PRO
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Documentation
Protein Ontology report - TGF-beta 2 isoform B
PR:000000405 -
http://purl.obolibrary.org/obo/PR_000000405
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000405
PRO name
TGF-beta 2 isoform B
Synonyms
PRO-Short-label
:
EXACT:
TGFB2/iso:B
Other
:
RELATED:
TGF-beta 2(442) | TGFB2 isoform B
Definition
"A TGF-beta 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P61812-2
or a 1:1 ortholog thereof." [
PMID:16868931
,
PMID:1777240
,
PMID:2850146
, PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000183
TGF-beta 2
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
1
Modification
3
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000000405
TGF-beta 2 isoform B, TGFB2/iso:B
organism-sequence
PR:P61812-2
transforming growth factor beta-2 isoform B (human), hTGFB2/iso:B
Yes
organism-modification
PR:000036534
TGF-beta 2 isoform B cleaved 1 (human), hTGFB2/iso:B/Clv:1
Yes
organism-modification
PR:000036535
TGF-beta 2 isoform B cleaved 2 (human), hTGFB2/iso:B/Clv:2
Yes
modification
PR:000000632
TGF-beta 2 isoform B cleaved 1, TGFB2/iso:B/Clv:1
organism-modification
PR:000036534
TGF-beta 2 isoform B cleaved 1 (human), hTGFB2/iso:B/Clv:1
Yes
modification
PR:000021909
TGF-beta 2 isoform B, signal peptide removed form, TGFB2/iso:B/SigPep-
modification
PR:000000633
TGF-beta 2 isoform B cleaved 2, TGFB2/iso:B/Clv:2
organism-modification
PR:000036535
TGF-beta 2 isoform B cleaved 2 (human), hTGFB2/iso:B/Clv:2
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036534
hTGFB2/iso:B/Clv:1
UniProtKB:P61812-2, 331-442
"A TGF-beta 2 isoform B cleaved 1 in human. UniProtKB:P61812-2, 331-442." [PMID:1777240, PRO:CNA]
located_in
GO:0005615
extracellular space
PMID:1777240
PR:000036535
hTGFB2/iso:B/Clv:2
UniProtKB:P61812-2, 20-330, 331-442
"A TGF-beta 2 isoform B cleaved 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-2, 20-330, 331-442." [PMID:1777240, PRO:CNA]
located_in
GO:0005615
extracellular space
PMID:1777240
PR:P61812-2
hTGFB2/iso:B
"A TGF-beta 2 isoform B that is encoded in the genome of human." [PRO:CNA]
enables
GO:0046982
protein heterodimerization activity
PMID:17845732
located_in
GO:0045177
apical part of cell
PMID:17845732