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RACE-PRO
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Protein Ontology report - TGF-beta 3 isoform 1
PR:000000406 -
http://purl.obolibrary.org/obo/PR_000000406
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000406
PRO name
TGF-beta 3 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
TGFB3/iso:1
Definition
"A TGF-beta 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P10600-1
or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000184
TGF-beta 3
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
4
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000000406
TGF-beta 3 isoform 1, TGFB3/iso:1
organism-sequence
PR:P10600-1
transforming growth factor beta-3 isoform 1 (human), hTGFB3/iso:1
Yes
organism-modification
PR:000036536
TGF-beta 3 isoform 1 cleaved 1 (human), hTGFB3/iso:1/Clv:1
Yes
organism-sequence
PR:P17125-1
transforming growth factor beta-3 isoform 1 (mouse), mTGFB3/iso:1
Yes
organism-modification
PR:000036537
TGF-beta 3 isoform 1 cleaved 1 (mouse), mTGFB3/iso:1/Clv:1
Yes
organism-modification
PR:000036538
TGF-beta 3 isoform 1 cleaved 3 (mouse), mTGFB3/iso:1/Clv:3
Yes
modification
PR:000000634
TGF-beta 3 isoform 1 cleaved 1, TGFB3/iso:1/Clv:1
organism-modification
PR:000036536
TGF-beta 3 isoform 1 cleaved 1 (human), hTGFB3/iso:1/Clv:1
Yes
organism-modification
PR:000036537
TGF-beta 3 isoform 1 cleaved 1 (mouse), mTGFB3/iso:1/Clv:1
Yes
modification
PR:000021910
TGF-beta 3 isoform 1, signal peptide removed form, TGFB3/iso:1/SigPep-
modification
PR:000000635
TGF-beta 3 isoform 1 cleaved 2, TGFB3/iso:1/Clv:2
modification
PR:000000636
TGF-beta 3 isoform 1 cleaved 3, TGFB3/iso:1/Clv:3
organism-modification
PR:000036538
TGF-beta 3 isoform 1 cleaved 3 (mouse), mTGFB3/iso:1/Clv:3
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036536
hTGFB3/iso:1/Clv:1
UniProtKB:P10600-1, 301-412 | PRO_0000033797
"A TGF-beta 3 isoform 1 cleaved 1 in human. UniProtKB:P10600-1, 301-412." [PMID:18243111, PRO:CNA]
enables
GO:0005160
transforming growth factor beta receptor binding
PMID:18243111
GO:0042803
protein homodimerization activity
PMID:18243111
PR:000036537
mTGFB3/iso:1/Clv:1
UniProtKB:P17125-1, 299-410 | PRO_0000033799
"A TGF-beta 3 isoform 1 cleaved 1 in mouse. UniProtKB:P17125-1, 299-410." [PMID:1821856, PRO:CNA]
acts_upstream_of_or_within
GO:0030879
mammary gland development
PMID:1821856
PR:000036538
mTGFB3/iso:1/Clv:3
UniProtKB:P17125-1, 30-298, 299-410
"A TGF-beta 3 isoform 1 cleaved 3 in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P17125-1, 30-298, 299-410." [PMID:1821856, PRO:CNA, PRO:DAN]
acts_upstream_of_or_within
GO:0030879
mammary gland development
PMID:1821856
PR:P10600-1
hTGFB3/iso:1
"A TGF-beta 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
acts_upstream_of_or_within
GO:0007165
signal transduction
PMID:3164476
GO:0007267
cell-cell signaling
PMID:3164476
PR:P17125-1
mTGFB3/iso:1
"A TGF-beta 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
acts_upstream_of_or_within
GO:0030879
mammary gland development
PMID:1821856
