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Protein Ontology report - TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form
PR:000000408 -
http://purl.obolibrary.org/obo/PR_000000408
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000408
PRO name
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form
Synonyms
PRO-Short-label
:
EXACT:
TGFBR1/iso:1/SigPep-/PhosRes+
Definition
"A TGF-beta receptor type-1 isoform 1, signal peptide removed form that includes at least one phosphorylated residue." [PRO:CNA]
PRO Category
modification
Parent
PR:000000522
TGF-beta receptor type-1 isoform 1, signal peptide removed form
PR:000037070
phosphoprotein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
3
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000408
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form, TGFBR1/iso:1/SigPep-/PhosRes+
modification
PR:000000523
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1, TGFBR1/iso:1/SigPep-/Phos:1
Yes
organism-modification
PR:000025959
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human), hTGFBR1/iso:1/SigPep-/Phos:1
Yes
Yes
organism-modification
PR:000036434
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse), mTGFBR1/iso:1/SigPep-/Phos:1
Yes
modification
PR:000003173
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated and ubiquitinated form, TGFBR1/iso:1/SigPep-/PhosUbiq+
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TGFBR1/iso:1/SigPep-/PhosRes+
forms found in complexes
TGFBR1/iso:1/SigPep-/PhosRes+
Component
Complexes
PR:000000523
TGFBR1/iso:1/SigPep-/Phos:1
PR:000025975
transforming growth factor beta type I receptor homodimeric complex phosphorylated form
PR:000025959
hTGFBR1/iso:1/SigPep-/Phos:1
PR:000025961
transforming growth factor beta type I receptor homodimeric complex phosphorylated form (human)
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000025959
hTGFBR1/iso:1/SigPep-/Phos:1
UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047 | PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047
"A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in human. Phosphorylation occurs by the action of active TGF-beta receptor type-2 within the GS-motifs. UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047." [PMID:7774578, PMID:8947046]
acts_upstream_of_or_within
GO:0006468
protein phosphorylation
PMID:7774578
GO:0007165
signal transduction
PMID:8242743
GO:0007181
transforming growth factor beta receptor complex assembly
PMID:8947046
enables
GO:0005025
transforming growth factor beta receptor activity, type I
PMID:7774578
;
PMID:8947046
located_in
GO:0005886
plasma membrane
PMID:8947046
PR:000036434
mTGFBR1/iso:1/SigPep-/Phos:1
UniProtKB:Q64729-1, 23-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047
"A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in mouse. UniProtKB:Q64729-1, 23-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047." [PMID:12065756, PRO:CNA]
acts_upstream_of_or_within
GO:0006468
protein phosphorylation
PMID:12065756
