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Protein Ontology report - smad7 isoform 1
PR:000000481 - http://purl.obolibrary.org/obo/PR_000000481
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000481   
  PRO namesmad7 isoform 1 
  Synonyms
PRO-Short-label: EXACT:SMAD7/iso:1
  Definition"A smad7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35253-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000374 smad7
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification6                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000481 smad7 isoform 1, SMAD7/iso:1

organism-sequence


PR:O15105-1 mothers against decapentaplegic homolog 7 isoform 1 (human), hSMAD7/iso:1
Yes
organism-modification


PR:000036565 smad7 isoform 1 acetylated 1 (human), hSMAD7/iso:1/Ac:1
Yes
organism-modification


PR:000036566 smad7 isoform 1 phosphorylated 1 (human), hSMAD7/iso:1/Phos:1

organism-sequence


PR:O35253-1 mothers against decapentaplegic homolog 7 isoform A (mouse), mSMAD7/iso:A

organism-modification


PR:000036932 smad7 isoform 1 phosphorylated 1 (mouse), mSMAD7/iso:1/Phos:1
Yes
organism-modification


PR:000049801 mothers against decapentaplegic homolog 7 isoform A monomethylated 1 (mouse), mSMAD7/iso:A/Me1:1

organism-modification


PR:000049802 mothers against decapentaplegic homolog 7 isoform A unmethylated 1 (mouse), mSMAD7/iso:A/UnMe:1

modification


PR:000000582 smad7 isoform 1 acetylated form, SMAD7/iso:1/AcRes+

modification


PR:000000663 smad7 isoform 1 acetylated 1, SMAD7/iso:1/Ac:1

organism-modification


PR:000036565 smad7 isoform 1 acetylated 1 (human), hSMAD7/iso:1/Ac:1
Yes
modification


PR:000000583 smad7 isoform 1 phosphorylated form, SMAD7/iso:1/PhosRes+

modification


PR:000000664 smad7 isoform 1 phosphorylated 1, SMAD7/iso:1/Phos:1

organism-modification


PR:000036566 smad7 isoform 1 phosphorylated 1 (human), hSMAD7/iso:1/Phos:1

organism-modification


PR:000036932 smad7 isoform 1 phosphorylated 1 (mouse), mSMAD7/iso:1/Phos:1
Yes
modification


PR:000000584 smad7 isoform 1 ubiquitinated form, SMAD7/iso:1/UbiqLys+

modification


PR:000000665 smad7 isoform 1 ubiquitinated 1, SMAD7/iso:1/Ubiq:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036565 hSMAD7/iso:1/Ac:1
UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064
"A smad7 isoform 1 acetylated 1 in human. UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064." [PMID:12408818, PRO:CNA]		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:12408818
enablesGO:0140416 transcription regulator inhibitor activity PMID:12408818
located_inGO:0005634 nucleus PMID:11278814
PR:000036932 mSMAD7/iso:1/Phos:1
UniProtKB:O35253-1, Ser-249, MOD:00046
"A smad7 isoform 1 phosphorylated 1 in mouse. UniProtKB:O35253-1, Ser-249, MOD:00046." [PMID:11278814, PRO:CNA]		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:11278814
enablesGO:0140416 transcription regulator inhibitor activity PMID:11278814
located_inGO:0005634 nucleus PMID:11278814
PR:O15105-1 hSMAD7/iso:1

"A smad7 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006950 response to stress PMID:9256479
GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10823886; PMID:9215638
enablesGO:0005515 protein binding PMID:9256479
GO:0140416 transcription regulator inhibitor activity PMID:9215638
located_inGO:0005634 nucleus PMID:11278814