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Protein Ontology report - c-myc protein isoform 1 phosphorylated 2
PR:000000538 - http://purl.obolibrary.org/obo/PR_000000538
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000538   
  PRO namec-myc protein isoform 1 phosphorylated 2 
  Synonyms
PRO-Short-label: EXACT:MYC/iso:1/Phos:2
  Definition"A c-myc protein isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser and Thr residues within the L[LY]PTLTPPLS sequence of the Myc box I within the amino-terminal regulatory domain, by ERK and GSK3, respectively. Example: UniProtKB:P01106-1, Thr-58, MOD:00047|Ser-62, MOD:00046." [PMID:14563837, PMID:8386367] 
  CommentNote: This form is not stable and is degraded through the proteosome pathway. 
  PRO Categorymodification 
  ParentPR:000000422 c-myc protein isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000000538 c-myc protein isoform 1 phosphorylated 2, MYC/iso:1/Phos:2

organism-modification


PR:000026053 c-myc protein isoform 1 phosphorylated 2 (mouse), mMYC/iso:1/Phos:2
Yes
organism-modification


PR:000026054 c-myc protein isoform 1 phosphorylated 2 (human), hMYC/iso:1/Phos:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026053 mMYC/iso:1/Phos:2
UniProtKB:P01108-1, Thr-58, MOD:00047|Ser-62, MOD:00046
"A c-myc protein isoform 1 phosphorylated 2 in mouse. UniProtKB:P01108-1, Thr-58, MOD:00047|Ser-62, MOD:00046." [PMID:14563837, PMID:15503302]		 located_inGO:0005634 nucleus PMID:14563837; PMID:15503302
PR:000026054 hMYC/iso:1/Phos:2
UniProtKB:P01106-1, Thr-58, MOD:00047|Ser-62, MOD:00046
"A c-myc protein isoform 1 phosphorylated 2 in human. UniProtKB:P01106-1, Thr-58, MOD:00047|Ser-62, MOD:00046." [PMID:7623799]		 enablesNOT GO:0003700 DNA-binding transcription factor activity PMID:7623799