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Protein Ontology report - retinoblastoma-like protein 2 isoform 1 phosphorylated 3
PR:000000562 -
http://purl.obolibrary.org/obo/PR_000000562
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000562
PRO name
retinoblastoma-like protein 2 isoform 1 phosphorylated 3
Synonyms
PRO-Short-label
:
EXACT:
RBL2/iso:1/Phos:3
Definition
"A retinoblastoma-like protein 2 isoform 1 that has been phosphorylated on residues at positions equivalent to Ser-639, Ser-952, Ser-966, Ser-971, Ser-972, Ser-973, Thr-974, Ser-981, Ser-982, and Thr-986 of the amino acid sequence represented by
UniProtKB:Q08999-1
or a 1:1 ortholog thereof. Example:
UniProtKB:Q08999-1
, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982,
MOD:00046
|Thr-974/Thr-986,
MOD:00047
." [PRO:CNA, PRO:DAN]
Comment
Note: This is the form observed in quiescent cells.
PRO Category
modification
Parent
PR:000000459
retinoblastoma-like protein 2 isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000562
retinoblastoma-like protein 2 isoform 1 phosphorylated 3, RBL2/iso:1/Phos:3
organism-modification
PR:000036473
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human), hRBL2/iso:1/Phos:3
Yes
organism-modification
PR:000036474
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse), mRBL2/iso:1/Phos:3
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036473
hRBL2/iso:1/Phos:3
UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in human. UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
acts_upstream_of_or_within
GO:0051726
regulation of cell cycle
PMID:11042701
;
PMID:11157749
;
PMID:8710362
enables
GO:0005515
protein binding
with
PR:Q16254
E2F-4 (human)
PMID:11042701
;
PMID:11157749
PR:000036474
mRBL2/iso:1/Phos:3
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in mouse." [PMID:10082561, PRO:CNA]
located_in
GO:0005667
transcription factor complex
PMID:10082561