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Protein Ontology report - thrombospondin-1 isoform 1, signal peptide removed glycosylated form
PR:000000589 -
http://purl.obolibrary.org/obo/PR_000000589
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000589
PRO name
thrombospondin-1 isoform 1, signal peptide removed glycosylated form
Synonyms
PRO-Short-label
:
EXACT:
THBS1/iso:1/SigPep-/GlycoRes+
Other
:
EXACT:
thrombospondin-1 isoform 1 cleaved and glycosylated 1
Definition
"A thrombospondin-1 isoform 1, signal peptide removed form that has been post-translationally modified to include C-mannosylation on WxxW patterns, and O-fucosylation in CSx[ST]CG motif." [
PMID:11067851
, PRO:CNA]
PRO Category
modification
Parent
PR:000000587
thrombospondin-1 isoform 1, signal peptide removed form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000589
thrombospondin-1 isoform 1, signal peptide removed glycosylated form, THBS1/iso:1/SigPep-/GlycoRes+
organism-modification
PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse), mTHBS1/iso:1/SigPep-/GlycoRes+
Yes
organism-modification
PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human), hTHBS1/iso:1/SigPep-/Glyco:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036487
mTHBS1/iso:1/SigPep-/GlycoRes+
UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813 | PRO_0000035843, MOD:00222|MOD:00812|MOD:00813
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
enables
GO:0005515
protein binding
with
PR:000036486
mTHBS1/iso:1/Clv:2
PMID:1459996
GO:0050431
transforming growth factor beta binding
PMID:9657149
located_in
GO:0005615
extracellular space
PMID:9657149
PR:000036488
hTHBS1/iso:1/SigPep-/Glyco:1
UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813 | PRO_0000035842, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
enables
GO:0005515
protein binding
with
PR:000028966
hTHBS1/iso:1/Clv:2
PMID:3305519
GO:0050431
transforming growth factor beta binding
PMID:15342643
