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Protein Ontology report - GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1
PR:000000615 -
http://purl.obolibrary.org/obo/PR_000000615
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000615
PRO name
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1
Synonyms
PRO-Short-label
:
EXACT:
RHOA/iso:1/IpCysEst:1
Definition
"A GTP-binding protein RhoA isoform 1 that has been geranylgeranylated on the Cys residue within the C-terminal CaaX motif (a=an aliphatic residue, X=any residue), followed by cleavage of aaX and methylation of the Cys. Example:
UniProtKB:P61586-1
, 1-190, Cys-190,
MOD:01119
." [
PMID:16773203
,
PMID:1905729
, PRO:CNA]
PRO Category
modification
Parent
PR:000000395
GTP-binding protein RhoA isoform 1
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000615
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1, RHOA/iso:1/IpCysEst:1
organism-modification
PR:000036520
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (human), hRHOA/iso:1/IpCysEst:1
Yes
organism-modification
PR:000036521
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (cow), cow-RHOA/iso:1/IpCysEst:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036520
hRHOA/iso:1/IpCysEst:1
UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119 | PRO_0000030411, Cys-190, MOD:01119
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 in human. UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:1383236, PMID:16773203, PRO:CNA, PRO:DAN]
acts_upstream_of_or_within
GO:0030036
actin cytoskeleton organization
PMID:16773203
GO:0043123
positive regulation of canonical NF-kappaB signal transduction
PMID:12761501
GO:1901224
positive regulation of non-canonical NF-kappaB signal transduction
PMID:12761501
located_in
GO:0005886
plasma membrane
PMID:16773203
PR:000036521
cow-RHOA/iso:1/IpCysEst:1
UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119 | PRO_0000030407, Cys-190, MOD:01119
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 in cow. UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119." [PMID:1903193, PRO:CNA, PRO:DAN]
located_in
GO:0005886
plasma membrane
PMID:1903193