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Protein Ontology report - TGF-beta 1 sequence variant C225R cleaved 1 (human) PR:000000625 - http://purl.obolibrary.org/obo/PR_000000625        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000000625      PRO name TGF-beta 1 sequence variant C225R cleaved 1 (human)    Synonyms PRO-Short-label: EXACT: hTGFB1/var:C225R/Clv:1 PRO-proteoform-std: EXACT: UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952 Other: EXACT: TGF-beta 1 sequence variant 6 cleaved 1 (human)   Definition "A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952." [PRO:CNA, PRO:DAN]    PRO Category organism-modification    Parent PR:000018292 TGF-beta 1 proteolytic cleavage product PR:000021906 TGF-beta 1 sequence variant C225R, signal peptide removed form (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000000625 hTGFB1/var:C225R/Clv:1 UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952 | TGF-beta 1 sequence variant 6 cleaved 1 (human) "A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952." [PRO:CNA, PRO:DAN] enables increased GO:0008083 growth factor activity relative to PR:000000616 TGF-beta 1 active protein PMID:11062463; PMID:12493741; PMID:12843182 located_in GO:0005615 extracellular space PMID:11062463; PMID:12493741; PMID:12843182