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Protein Ontology report - TGF-beta 2 isoform A cleaved 1
PR:000000629 - http://purl.obolibrary.org/obo/PR_000000629
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000629   
  PRO nameTGF-beta 2 isoform A cleaved 1 
  Synonyms
PRO-Short-label: EXACT:TGFB2/iso:A/Clv:1
Other: RELATED:TGF-beta 2 mature protein
  Definition"A TGF-beta 2 isoform A that has been processed by proteolytic cleavage and released from the latent complex. This form, cross-linked to an identical chain, is the active mature protein." [PMID:3476488] 
  PRO Categorymodification 
  ParentPR:000000404 TGF-beta 2 isoform A
PR:000018293 TGF-beta 2 proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000000629 TGF-beta 2 isoform A cleaved 1, TGFB2/iso:A/Clv:1

organism-modification


PR:000036530 TGF-beta 2 isoform A cleaved 1 (human), hTGFB2/iso:A/Clv:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036530 hTGFB2/iso:A/Clv:1
UniProtKB:P61812-1, 303-414 | PRO_0000033785
"A TGF-beta 2 isoform A cleaved 1 in human. UniProtKB:P61812-1, 303-414." [PMID:15944186, PMID:16227582, PMID:2119582, PMID:3162913, PMID:3476488, PRO:CNA]		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:3162913
GO:0008285 negative regulation of cell population proliferation PMID:15944186
enablesGO:0001540 amyloid-beta binding PMID:16227582
GO:0005160 transforming growth factor beta receptor binding PMID:16227582
GO:0042803 protein homodimerization activity PMID:2119582; PMID:3476488
located_inGO:0005615 extracellular space PMID:3162913