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Protein Ontology report - activin/inhibin beta A chain isoform 1 cleaved 1
PR:000000637 - http://purl.obolibrary.org/obo/PR_000000637
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000637   
  PRO nameactivin/inhibin beta A chain isoform 1 cleaved 1 
  Synonyms
PRO-Short-label: EXACT:INHBA/iso:1/Clv:1
  Definition"An activin/inhibin beta A chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide, yielding the mature protein. It is a subunit of inhibin A and activin A complexes. Inhibin A complex is a dimer of INHA and INHBA, whereas activin A complex is a homodimer of INHBA." [PMID:15948132] 
  PRO Categorymodification 
  ParentPR:000021911 activin/inhibin beta A chain isoform 1, signal peptide removed form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000000637 activin/inhibin beta A chain isoform 1 cleaved 1, INHBA/iso:1/Clv:1

organism-modification


PR:000036539 activin/inhibin beta A chain isoform 1 cleaved 1 (mouse), mINHBA/iso:1/Clv:1
Yes
organism-modification


PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human), hINHBA/iso:1/Clv:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036539 mINHBA/iso:1/Clv:1
UniProtKB:Q04998-1, 309-424 | PRO_0000033711
"An activin/inhibin beta A chain isoform 1 cleaved 1 in mouse. UniProtKB:Q04998-1, 309-424." [PMID:1646080, PMID:2133547, PMID:7577669, PRO:CNA]		 enablescontributes_to GO:0005102 signaling receptor binding PMID:1646080; PMID:7577669
GO:0046983 protein dimerization activity PMID:2133547
PR:000036540 hINHBA/iso:1/Clv:1
UniProtKB:P08476-1, 311-426 | PRO_0000033709
"An activin/inhibin beta A chain isoform 1 cleaved 1 in human. UniProtKB:P08476-1, 311-426." [PMID:10320815, PMID:12213882, PMID:12456957, PMID:12960042, PMID:1537316, PMID:17456790, PMID:2575216, PMID:7890768, PMID:9884026, PRO:CNA]		 acts_upstream_of_or_withinGO:0007166 cell surface receptor signaling pathway PMID:12456957
GO:0007267 cell-cell signaling PMID:12456957
GO:0009605 response to external stimulus PMID:10320815
GO:0030154 cell differentiation PMID:12456957
GO:0032925 regulation of activin receptor signaling pathway PMID:9884026
enablescontributes_to GO:0005102 signaling receptor binding PMID:7890768
GO:0046983 protein dimerization activity PMID:1537316
located_inGO:0005576 extracellular region PMID:12213882; PMID:2575216
GO:0032991 protein-containing complex PMID:12960042
GO:0043509 activin A complex PMID:7890768
GO:0043512 inhibin A complex PMID:17456790; PMID:7890768