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Protein Ontology report - smad3 isoform 1 acetylated and phosphorylated 1
PR:000000657 - http://purl.obolibrary.org/obo/PR_000000657
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000657   
  PRO namesmad3 isoform 1 acetylated and phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:SMAD3/iso:1/AcPhos:1
  Definition"A smad3 isoform 1 acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated at a Lys residue within the MH1 domain by coactivators, such as CBP and EP300. Example: UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046." [PMID:17074756
  PRO Categorymodification 
  ParentPR:000000577
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
modification



PR:000000657 smad3 isoform 1 acetylated and phosphorylated 1, SMAD3/iso:1/AcPhos:1


organism-modification



PR:000036557 smad3 isoform 1 acetylated and phosphorylated 1 (human), hSMAD3/iso:1/AcPhos:1

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036557
hSMAD3/iso:1/AcPhos:1
UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046
acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:17074756
enablesGO:0003700 DNA-binding transcription factor activity PMID:17074756
located_inGO:0005634 nucleus PMID:17074756