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RACE-PRO
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Protein Ontology report - smad5 isoform 1 phosphorylated 1
PR:000000661 -
http://purl.obolibrary.org/obo/PR_000000661
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000661
PRO name
smad5 isoform 1 phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
SMAD5/iso:1/Phos:1
Definition
"A smad5 isoform 1 phosphorylated form in which the phosphorylation occurs at the C-terminal SSxS motif as a result of the activation of the bone morphogenetic protein (BMP) signaling pathway. Example:
UniProtKB:Q99717-1
, Ser-463/Ser-465,
MOD:00046
." [
PMID:8637600
]
PRO Category
modification
Parent
PR:000000580
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000661
smad5 isoform 1 phosphorylated 1, SMAD5/iso:1/Phos:1
organism-modification
PR:000036562
smad5 isoform 1 phosphorylated 1 (human), hSMAD5/iso:1/Phos:1
Yes
organism-modification
PR:000036563
smad5 isoform 1 phosphorylated 1 (mouse), mSMAD5/iso:1/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036562
hSMAD5/iso:1/Phos:1
UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046
acts_upstream_of_or_within
GO:0030509
BMP signaling pathway
PMID:8637600
enables
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
PMID:8673135
PR:000036563
mSMAD5/iso:1/Phos:1
UniProtKB:P97454-1, Ser-463/Ser-465, MOD:00046
acts_upstream_of_or_within
GO:0030509
BMP signaling pathway
PMID:16522160
located_in
GO:0005634
nucleus
PMID:10504300
;
PMID:9759503
