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Protein Ontology report - cation channel sperm-associated auxiliary subunit beta
PR:000000672 - http://purl.obolibrary.org/obo/PR_000000672
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000672   
  PRO namecation channel sperm-associated auxiliary subunit beta 
  Synonyms
PRO-Short-label: EXACT:CATSPERB
Gene-based: RELATED:C14orf161
Other: EXACT:CatSper-beta
  Definition"A protein that is a translation product of the human CATSPERB gene or a 1:1 ortholog thereof. Members of this class are auxiliary proteins to the CatSper channel. They have four putative transmembrane-spanning domains. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel." [PMID:17478420, PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038543
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000672 cation channel sperm-associated auxiliary subunit beta, CATSPERB

organism-gene


PR:A2RTF1 cation channel sperm-associated auxiliary subunit beta (mouse), mCATSPERB

organism-sequence


PR:A2RTF1-1 cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse), mCATSPERB/iso:1
Yes
organism-gene


PR:Q9H7T0 cation channel sperm-associated auxiliary subunit beta (human), hCATSPERB

organism-sequence


PR:Q9H7T0-1 cation channel sperm-associated auxiliary subunit beta isoform 1 (human), hCATSPERB/iso:1

organism-sequence


PR:Q9H7T0-2 cation channel sperm-associated auxiliary subunit beta isoform h2 (human), hCATSPERB/iso:h2

sequence


PR:000000695 cation channel sperm-associated auxiliary subunit beta isoform 1, CATSPERB/iso:1

organism-sequence


PR:A2RTF1-1 cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse), mCATSPERB/iso:1
Yes
organism-sequence


PR:Q9H7T0-1 cation channel sperm-associated auxiliary subunit beta isoform 1 (human), hCATSPERB/iso:1

modification


PR:000002588 cation channel sperm-associated auxiliary subunit beta isoform 1 unmodified form, CATSPERB/iso:1/UnMod

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:A2RTF1-1 mCATSPERB/iso:1

"A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of mouse." [PRO:CNA]		 located_inGO:0032991 protein-containing complex PMID:17478420