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Protein Ontology report - cGMP-gated cation channel alpha-1 isoform 1
PR:000000737 -
http://purl.obolibrary.org/obo/PR_000000737
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000737
PRO name
cGMP-gated cation channel alpha-1 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
CNGA1/iso:1
Definition
"A cGMP-gated cation channel alpha-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P29973-1
or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000686
cGMP-gated cation channel alpha-1
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
3
Modification
3
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000000737
cGMP-gated cation channel alpha-1 isoform 1, CNGA1/iso:1
organism-sequence
PR:P29973-1
cGMP-gated cation channel alpha-1 isoform 1 (human), hCNGA1/iso:1
Yes
organism-sequence
PR:P29974-1
cGMP-gated cation channel alpha-1 isoform 1 (mouse), mCNGA1/iso:1
organism-sequence
PR:Q00194-1
cGMP-gated cation channel alpha-1 isoform 1 (cow), cow-CNGA1/iso:1
Yes
organism-modification
PR:000036569
cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 1 (cow), cow-CNGA1/iso:1/Phos:1
Yes
organism-modification
PR:000045379
cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 2 (cow), cow-CNGA1/iso:1/Phos:2
organism-modification
PR:000045381
cGMP-gated cation channel alpha-1 isoform 1 unphosphorylated 1 (cow), cow-CNGA1/iso:1/UnPhos:1
Yes
modification
PR:000000932
cGMP-gated cation channel alpha-1 isoform 1 phosphorylated form, CNGA1/iso:1/PhosRes+
modification
PR:000000981
cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 1, CNGA1/iso:1/Phos:1
organism-modification
PR:000036569
cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 1 (cow), cow-CNGA1/iso:1/Phos:1
Yes
modification
PR:000045378
cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 2, CNGA1/iso:1/Phos:2
organism-modification
PR:000045379
cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 2 (cow), cow-CNGA1/iso:1/Phos:2
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036569
cow-CNGA1/iso:1/Phos:1
UniProtKB:Q00194-1, Tyr-498, MOD:00048
"A cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 1 in cow. UniProtKB:Q00194-1, Tyr-498, MOD:00048." [PMID:10366613, PMID:14602825, PRO:CNA]
enables
decreased
GO:0030553
cGMP binding
relative to
PR:000002593
PMID:10366613
PR:000045381
cow-CNGA1/iso:1/UnPhos:1
UniProtKB:Q00194-1, Tyr-498, PR:000026291
"A cGMP-gated cation channel alpha-1 isoform 1 (cow) that lacks phosphorylation on Tyr-498. UniProtKB:Q00194-1, Tyr-498, PR:000026291." [PMID:10366613, PRO:CNA]
enables
GO:0030553
cGMP binding
PMID:10366613
PR:P29973-1
hCNGA1/iso:1
"A cGMP-gated cation channel alpha-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
located_in
GO:0005886
plasma membrane
PMID:7479749
PR:Q00194-1
cow-CNGA1/iso:1
"A cGMP-gated cation channel alpha-1 isoform 1 that is encoded in the genome of cow." [PRO:CNA]
located_in
GO:0017071
intracellular cyclic nucleotide activated cation channel complex
PMID:12432397
;
PMID:12467591
