|
PRO ID
|
|
PRO name | voltage-gated potassium channel subunit KCNQ2 isoform 6 |
Synonyms | PRO-Short-label: | EXACT: | KCNQ2/iso:6 | Other: | RELATED: | HNSPC | |
Definition | "A voltage-gated potassium channel subunit KCNQ2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43526-6 or a 1:1 ortholog thereof." [PMID:9039501, PRO:CNA, PRO:DAN] |
Comment | Note: Inclusion of isoform 6 in heteromultimers results in attenuation of potassium current. Prominent expression of isoform 6 in the developing brain may alter firing repertoires of immature neurons excitability to provide cues for proliferation rather than differentiation. |
PRO Category | sequence |
Parent | PR:000000729 voltage-gated potassium channel subunit KCNQ2
|
Terms by PRO Category |
Organism-Independent |
Organism-Specific |
Category |
Number of Terms |
Category |
Number of Terms |
Sequence | 1 |
Organism-Sequence |
1 | Modification | 0 |
Organism-Modification |
0 | | | |
Term Hierarchy Visualization |
|